Functional polymeric nanopores from cyclic peptide templates

环肽模板的功能性聚合物纳米孔

• 批准号: DP140100241
• 负责人: Prof Katrina Jolliffe
• 金额: $ 33.56万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP140100241
• 关键词: Functional; polymeric; nanopores; cyclic; peptide

This research programme will develop nanotubes prepared through the self-assembly of cyclic peptide/polymer conjugates into functional devices for applications as nanopores. The project will establish the fundamental knowledge required to develop these materials into nanoporous polymeric films and transmembrane channels. The research programme will establish new synthetic routes to the conjugates, ascertain the technique of assembly into nanotubes, with a particular focus on improving the precision with which we achieve structural control, and explore the use of the nanotubes to design nanopores, for applications in the manufacture of nanoporous materials, as antibiotic agents and as biosensors.

本研究项目将开发通过环肽/聚合物偶联物自组装而成的纳米管，用于纳米孔的功能器件。该项目将建立将这些材料开发成纳米多孔聚合物薄膜和跨膜通道所需的基础知识。该研究项目将建立新的共轭物合成路线，确定组装成纳米管的技术，特别关注提高我们实现结构控制的精度，并探索利用纳米管设计纳米孔，用于制造纳米孔材料，作为抗生素剂和生物传感器。