Anion receptors with high selectivity in aqueous environments

在水环境中具有高选择性的阴离子受体

• 批准号: DP170100118
• 负责人: Prof Katrina Jolliffe
• 金额: $ 27.48万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2020-06-29
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP170100118
• 关键词: Anion; receptors; selectivity; aqueous; environments

This project aims to develop neutral anion receptors that can bind to anions such as chloride and sulphate both selectively and strongly in water and transport them across membranes. These receptors have uses in the environment and medicine. Available receptors are limited to organic solvents or cannot discriminate between anions. This project will design hydrogen bonding motifs and incorporate them into water-soluble macrocycles tailored to complement the size and shape of target anions. This project will provide innovative technologies for the detection of anionic species in areas including environmental (e.g. monitoring of sulphate levels in wastewater) and biomedical applications (e.g. detection of chloride concentrations in blood).

该项目旨在开发中性阴离子受体，可以在水中选择性和强烈地与氯离子和硫酸根等阴离子结合，并将其穿过膜。这些受体在环境和医学中有用途。可用的受体仅限于有机溶剂或不能区分阴离子。该项目将设计氢键基序，并将其纳入水溶性大环中，以补充目标阴离子的大小和形状。该项目将提供创新技术，用于检测环境（例如监测废水中的硫酸盐含量）和生物医学应用（例如检测血液中的氯化物浓度）等领域的阴离子物质。