DEVELOPMENT OF SCREENING METHOD FOR SIMIAN FOAMY VIRUS

绝经前的黑人女性患病率要高出2到3倍。 冠心病(CHD)高于绝经前白人女性。这个 这项研究的目的是为了更深入地了解原因 对于这一差异，目前尚不清楚。我们比较了CHD 99名黑人和100名白人健康绝经前妇女的危险因素 年龄在18岁到45岁之间，社会经济条件相对较好 状态。与白人女性相比，黑人女性的身体质量更高 指数(32.0-9.2vs29.0-9.4 kg/m2，p=0.021)和更高的收缩压 舒张压(79_14 Vs 75_)。 11毫米汞柱，p=0.048)血压。平均血浆脂蛋白(A) 黑人女性的浓度明显更高(40.2-31.3 Mg/dl)高于白人女性(19.2-23.7 mg/dl，p&lt；0.0001)。这个 黑人女性的血浆总同型半胱氨酸水平也较高 (8.80~3.38vs7.81~2.58umol/L，p=0.013)。黑人女性， 而血浆甘油三酯水平较低(0.91_0.46 vs 1.22_ 0.60mmo1/L，p&lt；0.0001)，并有更高密度的趋势 脂蛋白(HDL)胆固醇水平(1.37_0.34 vs 1.29_0.31 Mmo1/L，p=0.064)。血浆总密度和低密度 脂蛋白(LDL)的胆固醇水平相似，尽管 黑人女性摄入饱和脂肪和胆固醇。 吸烟率和饮酒率都很低，而且相似 在两场比赛之间。绝经前的黑人女性平均体型较高 体重指数、血压、脂蛋白(A)和血浆总 同型半胱氨酸水平，以及更多的饱和脂肪和 比白人女性的胆固醇含量高。这些在冠状动脉风险方面的差异 这些因素可能会使我们研究中的黑人女性面临更高的风险 冠心病与白人女性的比较。资助与Dr的合作 OHSU出版公司的Gerhard GT，Sexton G，Malinow先生，WINDER RC，Connor SL，Pappu AS，Connor We。绝经前的黑人女性有 与白人女性相比，患冠心病的风险因素更多。美国东部时间J 心脏82：1040-1045,1998。

Premenopausal black women have a 2- to 3-fold greater rate of coronary heart disease (CHD) than premenopausal white women. The purpose of this study was to provide greater insight into the reasons for this difference, which are currently unclear. We compared CHD risk factors in 99 black and 100 white, healthy, premenopausal women, aged 18 to 45 years, and of relatively advantaged socioeconomic status. Compared with white women, black women had a higher body mass index (32.0 _ 9.2 vs 29.0 _ 9.4 kg/m2, p=0.021), and higher systolic (124 _17 vs 115 _ 14 mm Hg, p<0.0001) and diastolic (79 _ 14 vs 75 _ 11 mm Hg, p=0.048) blood pressures. The mean plasma lipoprotein(a) concentration was markedly higher in the black women (40.2 _ 31.3 mg/dl) than in the white women (19.2 _ 23.7 mg/dl, p<0.0001). The plasma total homocysteine level was also higher in the black women (8.80 _ 3.38 vs 7.81 _ 2.58 umol/L, p=0.013). The black women, however, had lower plasma triglyceride levels (0.91 _ 0.46 vs 1.22 _ 0.60 mmol/L, p<0.0001), and a trend toward higher high-density lipoprotein (HDL) cholesterol levels (1.37 _ 0.34 vs 1.29 _ 0.31 mmol/L, p=0.064) than the white women. Plasma total and low-density lipoprotein (LDL) cholesterol levels were similar, despite a greater consumption of saturated fat and cholesterol by the black women. Rates of cigarette smoking and alcohol intake were low and similar between the races. Premenopausal black women had a higher mean body mass index, blood pressure, lipoprotein(a), and plasma total homocysteine level, and a greater consumption of saturated fat and cholesterol than white women. These differences in coronary risk factors may place the black women in our study at increased risk for CHD compared with the white women. FUNDING Collaboration with Dr. Gerhard at OHSU PUBLICATIONS Gerhard GT, Sexton G, Malinow MR, Wander RC, Connor SL, Pappu AS, Connor WE. Premenopausal black women have more risk factors for coronary heart disease than white women. Am J Cardiol 82:1040-1045, 1998.