OPERATION OF BEAMLINE X 9A RESOURCE DEDICATED TO TIME RESOLVED XRAY FOOTPRINTING
OPERATION OF BEAMLINE X 9A RESOURCE DEDICATED TO TIME RESOLVED XRAY FOOTPRINTING
批准号:
6345073
负责人:
MARK R CHANCE
金额:
$5.38万
依托单位国家:
美国
项目类别:
财政年份:
2000
资助国家:
美国
项目状态:
已结题
起止时间:
2000-09-01 至 2001-08-31
中文摘要
为了提供足迹技术的专用通道,
国家同步加速器光源的X9 A沿着与
一个专用的停流仪器,允许足迹研究,
我们扩大的调查小组 光束线接受高达5
毫弧度的白色光束,通量密度为109
光子/s/mm 2/0.07%带宽,有效能量范围为3-30
凯 专用的光束线对于激光器的高生产率是必要的。
核心和合作研究项目。 我们的资源是世界
该技术的领先者,并提供专用光束线
我们将继续在这一领域发挥领导作用。 我们现在经常
在5-10毫秒和更长的时间尺度上进行足迹研究
我们的断流装置 理解RNA的重大进展
蛋白质-DNA复合物的研究
组建已经启动。 专用足迹光束线
将于一九九九年年底迁往新车站(X28 C),
新的晶体学项目 资源已被赋予
NSLS访问新光束线。
英文摘要
To provide dedicated access to footprinting technology, beamline
X9A at the National Synchrotron Light Source is maintained along with
a dedicated stopped flow instrument to allow footprinting studies for
our expanded group of investigators. The beamline accepts up to 5
milliradians of white beam, with a flux density of 109
photons/s/mm2/0.07% bandwidth over an effective energy range of 3-30
keV. A dedicated beamline is necessary for high productivity of the
core and collaborative research project. Our Resource is the world
leader in this technology and the availability of a dedicated beamline
will continue our leadership in this area. We are now routinely
conducting footprinting studies on 5-10 msec and longer timescales
with our stopped flow device. Major advances in understanding RNA
folding have been accomplished and studies of protein-DNA complex
formation have been initiated. The dedicated footprinting beamline
will be moved to a new station (X28C) in late 1999 to make way for the
new crystallography program at X9A. The resource has been given
access to the new beamline by the NSLS.
期刊论文(0)
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科研奖励(0)
会议论文
Research Support Core C: Computational Biology in Substance Use
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批准号:10304585
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项目类别:
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依托单位:
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批准号:10632097
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依托单位:
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批准号:8265984
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依托单位:
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批准号:8070036
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项目类别:
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资助金额:$27.16万
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财政年份:2010
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负责人:MARK R CHANCE
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依托单位:
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批准号:8440819
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项目类别:
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负责人:MARK R CHANCE
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依托单位:
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批准号:7896398
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财政年份:2009
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依托单位:
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批准号:8936209
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依托单位:
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批准号:8053331
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项目类别:
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财政年份:2009
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财政年份:2009
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负责人:MARK R CHANCE
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项目类别:
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财政年份:2009
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负责人:MARK R CHANCE
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依托单位:
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批准号:8337422
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项目类别:
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负责人:MARK R CHANCE
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依托单位:
海外基金