TRANSIENT INFRARED SPECTROSCOPY

红外光谱学允许访问的振动水平 分子，从而允许研究在过程中形成的中间体 光学触发的事件。这项研究涉及到…的发展 用于蛋白质研究的高重复频率红外光谱分析 通过中间态的振动光谱来研究动力学。这个 这项工作的主旨是设计一种光学参数 使用硫代没食子酸银和镓的发生器/放大系统 硒化物晶体。目前正在实施的这一设计是 能够获取射程内的瞬时红外光谱 500到3000厘米-1。系统正在使用KTP和BBO OPA来填写 3000到10,000厘米-1的区域。这个激光系统能够 产生极短的可见光(20fS)和红外脉冲 (40f)辐射。此外，我们还耦合了32个元素的MCT 将探测器阵列多路传输到红外探头生成系统。 有了这个系统，就有了获取光谱的能力 相干红外信号的测量。这允许光谱 红外光子回波的分辨率，提供详细信息 多肽和蛋白质部分中的振动能流。在……里面 道达尔，我们正在开发泵浦/探测，瞬变光栅，光子回波 和外差光子回波方法作为超快推力的一部分 蛋白质的红外光谱分析。

Infrared spectroscopy allows access to the vibrational levels of molecules and thus permits the study of intermediates formed during optically triggered events. This research concerns the development of high repetition rate infrared spectroscopy aimed at studying protein dynamics via the vibrational spectra of the intermediate states. The thrust of this effort is the design of an optical parametric generator/amplifier system using silver thiogallate and gallium selenide crystals. This design, which is now being implemented, is enabling the acquisition of transient infrared spectra over the range 500 to 3000 cm-1. The system is using KTP and BBO OPA's to fill in the region from 3000 to 10,000 cm-1. This laser system is capable of generating extremely short pulses of visible (20fs) and infrared (40fs) radiation. In addition, we have coupled a 32 element MCT multiplexed detector array into the infrared probe generating system. With this system we have the capability of obtaining spectral measurements of coherent infrared signals. This allows for spectral resolution of infrared photon echoes, providing detailed information of vibrational energy flow within peptide and protein moieties. In total, we are developing pump/probe, transient grating, photon echo and heterodyned photon echo methods as part of the thrust in ultrafast infrared spectroscopy for proteins.