TRANSIENT INFRARED SPECTROSCOPY

红外光谱允许访问的振动水平， 分子，从而允许研究在过程中形成的中间体 光学触发事件 这项研究涉及的发展， 高重复率红外光谱法研究蛋白质 通过中间态的振动光谱的动力学。 的 这一努力的推力是光学参量的设计 使用硫代镓酸银和镓的发生器/放大器系统 硒化物晶体 目前正在实施的这一设计， 使得能够在所述范围内获得瞬时红外光谱 500至3000 cm-1。 系统正在使用KTP和BBO OPA来填充 从3000到10，000 cm-1的区域。 该激光系统能够 产生可见光（20 fs）和红外线的极短脉冲 （40 fs）辐射。 此外，我们还耦合了一个32元件的MCT 将多路复用检测器阵列引入红外探针生成系统中。 有了这个系统，我们有能力获得光谱 相干红外信号的测量。 这使得光谱 红外光子回波的分辨率，提供详细信息 振动能量在肽和蛋白质中的流动。 在 总的来说，我们正在开发泵/探针，瞬态光栅，光子回波 和外差光子回波方法作为超快推进的一部分， 蛋白质的红外光谱

Infrared spectroscopy allows access to the vibrational levels of molecules and thus permits the study of intermediates formed during optically triggered events. This research concerns the development of high repetition rate infrared spectroscopy aimed at studying protein dynamics via the vibrational spectra of the intermediate states. The thrust of this effort is the design of an optical parametric generator/amplifier system using silver thiogallate and gallium selenide crystals. This design, which is now being implemented, is enabling the acquisition of transient infrared spectra over the range 500 to 3000 cm-1. The system is using KTP and BBO OPA's to fill in the region from 3000 to 10,000 cm-1. This laser system is capable of generating extremely short pulses of visible (20fs) and infrared (40fs) radiation. In addition, we have coupled a 32 element MCT multiplexed detector array into the infrared probe generating system. With this system we have the capability of obtaining spectral measurements of coherent infrared signals. This allows for spectral resolution of infrared photon echoes, providing detailed information of vibrational energy flow within peptide and protein moieties. In total, we are developing pump/probe, transient grating, photon echo and heterodyned photon echo methods as part of the thrust in ultrafast infrared spectroscopy for proteins.