课题基金 / 基金详情

DETERMINATION OF THE STRUCTURE OF THE BACTERIAL RIBOSOME

DETERMINATION OF THE STRUCTURE OF THE BACTERIAL RIBOSOME
细菌核糖体结构的测定
批准号：
6346393
负责人：
PETER B. MOORE
金额：
$3.26万
依托单位：
BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB
依托单位国家：
美国
项目类别：
财政年份：
2000
资助国家：
美国
项目状态：
已结题
起止时间：
2000-09-01 至 2001-08-31
来源：
https://reporter.nih.gov/project-details/6346393
关键词：
bacteria bioimaging /biomedical imaging biological products biomedical resource genetics radiography radiology structural biology

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英文摘要
The goal of this research is the determination of the crystal structure of the bacterial ribosome. The crystal structure of the 50S subunit of Haloarcula marismortui, for which crystals are already in hand, will be pursued. Crystallization studies of 70S, 30S and 50S subunits from other bacterial sources will be undertaken, as will crystallization of domains of the 30S ribosomal subunit (E. coli). The structures will be determined of the crystals obtained.
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ANTIBIOTIC RESISTANCE MUTATIONS IN H MARISMORTUI 50S RIBOSOMAL SUBUNITS
Program in Macromolecular Structure, Motion, Control
  • 批准号：
    7529241
  • 项目类别：
  • 资助金额：
    $29.56万
  • 财政年份：
    2007
  • 负责人：
    PETER B. MOORE
  • 依托单位：
    YALE UNIVERSITY
ANTIBIOTIC RESISTANCE MUTATIONS IN H MARISMORTUI 50S RIBOSOMAL SUBUNITS
CORE Program in Macromolecular Structure, Motion, Control
  • 批准号：
    7529245
  • 项目类别：
  • 资助金额：
    $43.95万
  • 财政年份：
    2007
  • 负责人：
    PETER B. MOORE
  • 依托单位：
    YALE UNIVERSITY