CANCER PAIN AND ITS MANAGEMENT

说明：在过去三年中，该项目已：（1）进行 一系列评估疼痛及其治疗的多中心研究， 非少数民族和少数民族癌症患者，并确定风险因素 对于那些被索引为疼痛管理不良的患者，（2）制定了一个 一系列干预措施的临床试验， 关于疼痛及其管理的专业和患者行为，基于 在镇痛实践改变的模型上，（3）完善了我们对 疼痛评估措施以及疼痛严重程度与 疼痛对患者的影响，特别是文化的关系 和语言的疼痛报告，（4）证明的效用， 疼痛和疼痛治疗的国际合作研究， 治疗美国癌症患者，了解导致癌症的因素， 疼痛管理不善。 本资助期的研究目标将集中在减少 继续接受疼痛控制不足的患者人数。 这些研究将：（1）实施描述性和干预性研究 在NCI申办的协作组中进行的多中心研究中，（2） 继续开展国际癌症疼痛研究，评估癌症疼痛， 癌症疼痛的治疗和检验方法 管理，以及（3）将医疗决策方法纳入 建立评估疼痛和症状有效性的新方法 对照治疗。 所描述的研究将利用已建立的合作， 国际疼痛和肿瘤学研究人员，以及东部合作组织 肿瘤组，并与UTMD安德森发展新的合作关系 NCI资助的研究基地和放射治疗肿瘤组。

DESCRIPTION: During the last three years, this project has: (1) conducted a series of multi-center studies evaluating pain and its treatment, both with non-minority and minority cancer patients, and determined risk factors for those patients indexed as having poor pain management, (2) developed a sequence of clinical trials of interventions to change both health care professional and patient behavior regarding pain and its management, based on a model of analgesic practice change, (3) refined our understanding of pain assessment measures and the relationship between pain severity and the impact of pain on the patient, especially the relationship between culture and language on pain report, and (4) demonstrated the utility of collaborative international studies of pain and pain treatment for assessing and treating U.S. cancer patients and for understanding factors that lead to poor pain management. The research goals of this funding period will focus on methods to reduce the number of patients who continue to receive inadequate pain control. These studies will: (1) implement both descriptive and intervention studies in multi-center studies performed in NCI-sponsored collaborative groups, (2) continue international studies of cancer pain, its assessment and its treatment and test methods of modifying health care practice of cancer pain management, and (3) incorporate medical decision making methodology to establish new ways of evaluating the effectiveness of pain and symptom control therapies. The studies described will make use of established collaborations with international pain and oncologic investigators, and the Eastern Cooperative Oncology Group, and develop new collaborations with the UTMD Anderson NCI-funded research base and the Radiation Treatment Oncology Group.