LOCALIZED MEASUREMENTS OF HYPERPOLARIZED 3HE DIFFUSION & T2 IN GUINEA PIG LUNG

超极化 3HE 扩散的局部测量

• 批准号: 6348151
• 负责人: X J CHEN
• 金额: $ 2.25万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-01 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6348151
• 关键词: Mammalia; biomedical equipment development; biomedical resource; health care; human tissue; nuclear magnetic resonance spectroscopy; technology /technique

MR microscopy may contribute to understanding what happens when a foreign body is place in the body for purposes of either imaging or measuring the chemical environment. We will image, with implanted coils, the development of fibrous capsule on the silicone coating that surrounds the imaging coil. Imaging will be done at 1, 7, 14 and 28 days after implant. Following fixation, the coil and surrounding tissue will be removed and imaged ex vivo at higher resolution. Finally, the complex of fibrous capsule and coil will be imaged by conventional microscopy.

MR 显微镜可能有助于理解当 出于成像或成像目的而将异物放置在体内 测量化学环境。 我们将成像，植入 线圈，在有机硅涂层上开发纤维胶囊 围绕成像线圈。 成像将在 1、7、14 和 28 进行 植入后几天。 固定后，线圈和周围 组织将被移除并以更高分辨率进行离体成像。 最后，纤维囊和线圈的复合体将通过以下方式成像 传统显微镜。