CORE--ANIMAL AND SURGERY SERVICES

核心——动物和手术服务

• 批准号: 6323411
• 负责人: Alan F Sved
• 金额: $ 20.73万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-05-01 至 2001-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6323411
• 关键词: 6 hydroxydopamine; Macaca fascicularis; animal colony; biomedical facility; experimental brain lesion; laboratory rat; nervous system disorder diagnosis; neurochemistry; neurosurgery

This Core will supervise purchasing, housing, and behavioral testing of animals. In addition, 6-OHDA-induced lesions will be conducted under the supervision of the Core Director. Additional surgical procedures of general importance to the Program Project also will be developed and performed through the Core as the need arises. In a series of studies we will examine an alternative to the conventional mode of lesioning by employing an osmotic minipump to administer the 6-OHDA. The quality of the surgical work will be monitored via analyses conducted by the neurochemistry and histology services (Cores B and C). This Core should therefore greatly enhance the productivity of the Program, permitting us to integrate the results obtained by different components of the Program Project.

该核心将监督采购，住房和行为