TRAINING OF ARTHRITIS RESEARCH SCIENTISTS
关节炎研究科学家的培训
基本信息
- 批准号:6374780
- 负责人:
- 金额:$ 21.71万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:1976
- 资助国家:美国
- 起止时间:1976-07-01 至 2002-04-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
DESCRIPTION (from the application): This is a competitive renewal application for a Rheumatology Training Grant that was last funded in 1976. The goal of this Training Program is to prepare qualified individuals for careers as independent investigators in areas of basic and clinical research related to problems in rheumatic diseases. Eligible M.D. candidates will generally have completed their clinical training in Rheumatology and must demonstrate a strong interest in research and in an academic career. Eligible Ph.D. candidates will have received their Ph.D. degree in Molecular Genetics, Biochemistry, Cell Biology, Immunology, or a related area of the life sciences. The Training Program includes a structured series of basic science lectures and research conference designed to give trainees a conceptual framework in the relevant areas of biological sciences. M.D. trainees will also apply to be enrolled in a three month full time, intensive research training course offered by the University of Michigan Medical School. The laboratory training period will include at least two years of research experience, with minimum concurrent clinical commitments. All trainees will apply for individual externally funded fellowships, and the Training Program will be used to support trainees for one to two years until they are able to obtain external funding. The faculty mentors for this Training Program include eighteen M.D., Ph.D. and M.D./Ph.D. scientists with tenure track faculty appointment at the University of Michigan Medical School. Eleven of these faculty members have appointments in the Division of Rheumatology and seven are from other departments or divisions. Several faculty members have joint appointments in both clinical and basic science departments. The Training Program is also supported by collaborating faculty with clinical duties (both tenure track and non-tenure track), and by research faculty with non-tenure track appointments. The collaborating faculty will participate in the Training Program but will not serve as primary mentors for trainees. The areas of scientific expertise represented by the faculty mentors include immunology, biochemistry, cell biology, and molecular genetics, in fields of investigation related to current problems in rheumatic diseases. These research programs are supported by external research funding greater than $8 million and by more than 22,000 square feet of laboratory space. The Training Program benefits greatly from support of the University of Michigan Multipurpose Arthritis Center and the Specialized Center of Research in Rheumatoid Arthritis. There is close interaction with the training programs in Immunopathology, Geriatrics and Cellular and Molecular Biology. Emphasis over the past ten years on recruitment of outstanding female and minority trainees has resulted in graduation of such individuals into academic positions, and this emphasis will be continued. The University of Michigan Training Program in Rheumatology has a strong record of producing leaders in academic rheumatology and related areas of basic investigation. The faculty, facilities and training plan outlined in the current proposal should provide an excellent framework for augmenting these accomplishments.
描述(摘自申请表):这是风湿病培训补助金的竞争性续签申请,上一次资助该基金是在1976年。该培训计划的目标是培养合格的个人,使其成为与风湿病问题相关的基础和临床研究领域的独立研究人员。符合条件的医学博士候选人通常已完成风湿病学的临床培训,并必须对研究和学术事业表现出浓厚的兴趣。符合条件的博士候选人将获得分子遗传学、生物化学、细胞生物学、免疫学或生命科学相关领域的博士学位。培训方案包括一系列有组织的基础科学讲座和研究会议,旨在为学员提供生物科学相关领域的概念框架。医学博士学员还将申请参加密歇根大学医学院提供的为期三个月的全日制强化研究培训课程。实验室培训期间将包括至少两年的研究经验,并同时承担最低限度的临床承诺。所有学员将申请个人外部资助奖学金,培训计划将用于支持学员一到两年,直到他们能够获得外部资助。该培训计划的教师导师包括18名医学博士、博士和医学博士/博士科学家,他们在密歇根大学医学院获得终身教职。其中11名教职员工在风湿科任职,7名教职员工来自其他科室。几名教员在临床和基础科学系都有联合任命。该培训计划还得到了具有临床职责(终身教职和非终身教职)的合作教员以及具有非终身教职教职任命的研究教员的支持。合作教员将参与培训计划,但不会作为受训人员的主要导师。教师导师所代表的科学专业领域包括免疫学、生物化学、细胞生物学和分子遗传学,以及与风湿性疾病当前问题相关的研究领域。这些研究项目得到了超过800万美元的外部研究资金和超过22,000平方英尺的实验室空间的支持。该培训计划得益于密歇根大学多功能关节炎中心和类风湿性关节炎专业研究中心的支持。与免疫病理学、老年病学以及细胞和分子生物学方面的培训计划有密切的互动。在过去十年中,对招聘杰出女性和少数族裔受训人员的重视导致这些人毕业于学术职位,这一重点将继续下去。密歇根大学风湿学培训项目在风湿病学和相关基础研究领域有着卓越的领导地位。本提案中概述的师资、设施和培训计划应为扩大这些成就提供一个极好的框架。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Leslie J Crofford其他文献
Circadian relationships between interleukin (IL)-6 and hypothalamic-pituitary-adrenal axis hormones: failure of IL-6 to cause sustained hypercortisolism in patients with early untreated rheumatoid arthritis.
白细胞介素 (IL)-6 与下丘脑-垂体-肾上腺轴激素之间的昼夜关系:IL-6 未能导致早期未经治疗的类风湿性关节炎患者持续皮质醇增多症。
- DOI:
10.1210/jcem.82.4.3852 - 发表时间:
1997 - 期刊:
- 影响因子:0
- 作者:
Leslie J Crofford;K. Kalogeras;George Mastorakos;M. Magiakou;Jana Wells;Keith S. Kanik;P. W. Gold;G. P. Chrousos;Ronald L. Wilder - 通讯作者:
Ronald L. Wilder
The hypothalamic-pituitary-adrenal stress axis in fibromyalgia and chronic fatigue syndrome
- DOI:
10.1007/s003930050239 - 发表时间:
1998 - 期刊:
- 影响因子:0
- 作者:
Leslie J Crofford - 通讯作者:
Leslie J Crofford
Primer on the Rheumatic Diseases
风湿病入门
- DOI:
10.1001/jama.1953.63690040007008 - 发表时间:
1999 - 期刊:
- 影响因子:0
- 作者:
J. Klippel;John H. Stone;Leslie J Crofford;Patience H. White - 通讯作者:
Patience H. White
Do infectious agents cause rheumatoid arthritis?
传染源会引起类风湿性关节炎吗?
- DOI:
- 发表时间:
1991 - 期刊:
- 影响因子:4.2
- 作者:
Ronald L. Wilder;Leslie J Crofford - 通讯作者:
Leslie J Crofford
The neuroscience and endocrinology of fibromyalgia.
纤维肌痛的神经科学和内分泌学。
- DOI:
- 发表时间:
1997 - 期刊:
- 影响因子:0
- 作者:
S. Pillemer;Laurence A. Bradley;Leslie J Crofford;Harvey Moldofsky;G. P. Chrousos - 通讯作者:
G. P. Chrousos
Leslie J Crofford的其他文献
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{{ truncateString('Leslie J Crofford', 18)}}的其他基金
Fibromyalgia TENS in Physical Therapy Study (TIPS): an embedded pragmatic clinical trial
纤维肌痛 TENS 物理治疗研究 (TIPS):一项嵌入式实用临床试验
- 批准号:
10891041 - 财政年份:2023
- 资助金额:
$ 21.71万 - 项目类别:
Fibromyalgia TENS in Physical Therapy Study (TIPS):an embedded pragmatic clinical trial
纤维肌痛 TENS 物理治疗研究 (TIPS):一项嵌入式实用临床试验
- 批准号:
10701211 - 财政年份:2019
- 资助金额:
$ 21.71万 - 项目类别:
Fibromyalgia TENS in Physical Therapy Study (TIPS):an embedded pragmatic clinical trial
纤维肌痛 TENS 物理治疗研究 (TIPS):一项嵌入式实用临床试验
- 批准号:
10253306 - 财政年份:2019
- 资助金额:
$ 21.71万 - 项目类别:
Fibromyalgia TENS in Physical Therapy Study (TIPS): an embedded pragmatic clinical trial: Administrative Supplement
物理治疗研究 (TIPS) 中的纤维肌痛 TENS:一项嵌入式实用临床试验:行政补充
- 批准号:
10650569 - 财政年份:2019
- 资助金额:
$ 21.71万 - 项目类别:
Pain and Well-being in Older Women: The Roles of Activity and Motivation
老年女性的疼痛和健康:活动和动机的作用
- 批准号:
8532595 - 财政年份:2013
- 资助金额:
$ 21.71万 - 项目类别:
Pain and Well-being in Older Women: The Roles of Activity and Motivation
老年女性的疼痛和健康:活动和动机的作用
- 批准号:
8685860 - 财政年份:2013
- 资助金额:
$ 21.71万 - 项目类别:
Fibromyalgia Activity Study with TENS "FAST"
使用 TENS“FAST”进行纤维肌痛活动研究
- 批准号:
8652437 - 财政年份:2013
- 资助金额:
$ 21.71万 - 项目类别:
Fibromyalgia Activity Study with TENS "FAST"
使用 TENS“FAST”进行纤维肌痛活动研究
- 批准号:
8903698 - 财政年份:2013
- 资助金额:
$ 21.71万 - 项目类别:
Fibromyalgia Activity Study with TENS "FAST"
使用 TENS“FAST”进行纤维肌痛活动研究
- 批准号:
8505581 - 财政年份:2013
- 资助金额:
$ 21.71万 - 项目类别:
Fibromyalgia Activity Study with TENS "FAST"
使用 TENS“FAST”进行纤维肌痛活动研究
- 批准号:
9127091 - 财政年份:2013
- 资助金额:
$ 21.71万 - 项目类别:
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Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data
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