MASTER OF SCIENCE DEGREE IN CLINICAL INVESTIGATION

临床研究理学硕士学位

• 批准号: 6402723
• 负责人: MICHAEL J. LICHTENSTEIN
• 金额: $ 19.95万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-30 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6402723
• 关键词: Hispanic Americans; clinical research; curriculum; education evaluation /planning; ethics; experimental designs; health science research; minority health professional; postgraduate education; statistics /biometry; technical writing

In recent years, it has become obvious that there is a special need for investigators trained in clinical research. The biotechnology revolution has provided many possible avenues to improve 0ult, lives, but these advances require expertise in patient- oriented research for them to benefit mankind. We plan to use the resources we have in San Antonio to provide an innovative training program in clinical research to train young scientists, physicians, dentists, nurses and allied health professionals for successful careers in clinical investigation. We plan to do this through a new Master of Science Degree in Clinical Investigation (MSCI). The 'laboratory' for our trainees will be the General Clinical Research Center, which is an NIH-funded General Clinical Research Center located in one of our teaching hospitals. A special goal will be to increase the number of ethnically diverse students, particularly Mexican-Americans and other Hispanic groups, who will be trained in the conduct of clinical research. Once trained, graduates of this program will be expert in the design and conduct of patient-oriented research studies involving direct interactions between investigators and human subjects. The preceptors for this training program are faculty members with active programs in clinical research, molecular biology, protein chemistry and cell biology, and who have proven expertise in running successful research programs and in obtaining extramural grant support. Since MDs lack the formal didactic training characteristic of many Phi) programs, we have established an organized didactic program designed to prepare our trainees to function as future independent clinical researchers. Candidates enrolling in the MSCI program will complete a mentored research project over two years while participating in a highly integrated set of six didactic courses. The courses include: (a) Research Methodology (3 semesters); (b)Biostatistics (3 semesters); (c) Ethical Conduct of Research (I semester); (d) Integration of Molecular Biology into Clinical Research (l semester); (e) Data management, Quality Control, and Regulatory Issues (l semester); and (f) Scientific Writing (l semester). Our goal is to prepare investigators skilled in the conduct of outstanding clinical research in culturally diverse settings. MSCI program effectiveness will be ascertained by monitoring a cohesive set of five primary outcomes. These outcomes are: (a) the number of ethnically diverse trainees enrolled; (b) the number of enrolled students who attain their degrees; (c) the number of scientific peer-reviewed publications resulting from MSCI research projects; (d) the career paths chosen by the MSCI graduates; and (e) the success rate at which MSCI graduates compete for career development and research awards.

近年来，很明显，特别需要经过临床研究培训的研究人员。生物技术革命提供了许多可能的途径来改善老年人的生活，但这些进步需要以病人为导向的研究的专业知识，使他们造福于人类。我们计划利用我们在圣安东尼奥的资源，提供一个创新的临床研究培训计划，培训年轻的科学家，医生，牙医，护士和专职医疗人员在临床研究的成功职业生涯。我们计划通过新的临床研究理学硕士学位（MSCI）来实现这一目标。 我们的实习生的“实验室”将是综合临床研究中心，这是一个NIH资助的综合临床研究中心，位于我们的教学医院之一。一个特别的目标是增加种族多样性学生的数量，特别是墨西哥裔美国人和其他西班牙裔群体，他们将接受临床研究的培训。一旦接受培训，该计划的毕业生将成为设计和进行以患者为导向的研究的专家，这些研究涉及研究人员和人类受试者之间的直接互动。该培训计划的导师是在临床研究，分子生物学，蛋白质化学和细胞生物学方面具有活跃计划的教师，并且在运行成功的研究计划和获得校外资助方面具有公认的专业知识。由于医学博士缺乏许多Phi）项目所特有的正式教学培训，我们已经建立了一个有组织的教学计划，旨在培养我们的学员成为未来的独立临床研究者。参加MSCI课程的候选人将在两年内完成一个指导研究项目，同时参加一套高度集成的六门教学课程。这些课程包括：（a）研究方法（3个学期）;（B）生物统计学（3个学期）;（c）研究的道德行为（I学期）;（d）分子生物学与临床研究的整合（l学期）;（e）数据管理，质量控制和监管问题（l学期）;和（f）科学写作（l学期）。我们的目标是准备调查熟练的文化多样性环境中进行杰出的临床研究。MSCI计划的有效性将通过监测一组有凝聚力的五个主要成果来确定。这些成果是：（a）不同种族的学员人数;（B）获得学位的学员人数;（c）摩根士丹利资本国际研究项目产生的经同行评审的科学出版物的数量;（d）摩根士丹利资本国际毕业生选择的职业道路;以及（e）摩根士丹利资本国际毕业生竞争职业发展和研究奖项的成功率。