Dust-related disease in WA: asbestos, silica and diesel exposures, lifestyle factors and genetic predisposition.

西澳与灰尘相关的疾病：石棉、二氧化硅和柴油暴露、生活方式因素和遗传倾向。

• 批准号: nhmrc : 139047
• 负责人: A/Pr Gina Ambrosini
• 金额: $ 37.82万
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2001
• 资助国家: 澳大利亚
• 起止时间: 2001-01-01 至 2003-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/dust-related-disease-genetic-predisposition/98204
• 关键词: Dust; related; disease; WA; asbestos

This multi-factorial project will extend the follow-up of 4 large, established groups of people who have experienced significant exposure to asbestos, silica or diesel, either through their jobs, or environmentally. Mesothelioma, lung cancer and prostate cancer are common among these groups. The study will provide important information on the effects of different levels of exposure to these three cancer-causing agents, as well as their effects on chronic respiratory diseases such as asbestosis, silicosis, asthma and tuberculosis. Ways in which these diseases may be prevented through the diet and other lifestyle habits (including smoking, alcohol consumption and exercise), will be closely examined. This study will also help to identify the genes which may place some people at a higher risk than others.

这个多因素项目将扩大对4个大型、成熟的人群的跟踪调查，这些人在工作中或在环境中经历了大量接触石棉、二氧化硅或柴油的情况。间皮瘤、肺癌和前列腺癌在这些人群中很常见。这项研究将提供有关不同程度接触这三种致癌物质的影响，以及它们对石棉肺、矽肺、哮喘和结核病等慢性呼吸系统疾病的影响的重要信息。将仔细研究通过饮食和其他生活习惯(包括吸烟、饮酒和锻炼)预防这些疾病的方法。这项研究还将有助于识别可能将某些人置于比其他人更高风险的基因。