COST EFFECTIVENESS OF DEVELOPING COUNTRY HIV PREVENTION

发展中国家艾滋病毒预防的成本效益

• 批准号: 6392251
• 负责人: Michael D Sweat
• 金额: $ 10.42万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 2003-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6392251
• 关键词: AIDS education /prevention; Africa; Caribbean islands; health behavior; health care cost /financing; health care service evaluation; health services research tag; human data; human population study; mathematical model; model design /development; sexually transmitted diseases; southeast Asia

DESCRIPTION (Applicant's Abstract): There is currently limited consensus on the most effective intervention designs for HIV prevention in developing countries. Decisions on which type of projects to fund, who should be targeted with interventions, and how to design prevention programs have not been based on comparisons of the cost-effectiveness of interventions. A major problem in forging consensus on these issues is that available data do not link costs to effectiveness measures. Standardization of costs and outcomes across populations, regions, and interventions has also been unavailable. This project will calculate and compare standardized measures of the cost-effectiveness of interventions for prevention of HIV and Sexually Transmitted Infections (STI) across types of interventions, geographic regions,and target populations using data from actual HIV/STI intervention projects in Africa, Latin America, and Asia. The sex projects selected for evaluation are all associated with the AIDSCAP project, funded by the US Agency of International Development, and include: (1) a comprehensive sex worker intervention in the Dominican Republic, (2) a peer-education and counseling intervention for men who have sex with men in the Dominican Republic, (3) a STD and peer-education intervention for sex workers in Tanzania, (4) a community-based prevention program in rural Tanzania, (5) a factory worker intervention in Thailand, and (6) a comprehensive HIV and STD intervention targeting poor women in Bangkok, Thailand. Comprehensive and standardized behavioral evaluation data are available for all sites, and cost data will be collected in the initial phase of the project. Retrospective control data on similarly unexposed populations will also be compiled and analyzed for each intervention site. The primary outcome of interest in the discounted cost per HIV case averted, and the cost per Quality Adjusted Life Year (QALY) for each intervention. This project will also help develop the applicant's skills and experience in conducting modeling and health economic analysis.

描述（申请人的摘要）：目前对于以下问题达成的共识有限 发展中国家艾滋病毒预防最有效的干预设计 国家。 决定资助哪种类型的项目、谁应该资助 干预措施的针对性以及如何设计预防方案尚未 是基于干预措施成本效益的比较。 一个 就这些问题达成共识的主要问题是现有数据确实 不将成本与有效性措施挂钩。 成本标准化 跨人群、跨地区和跨干预措施的结果也 不可用。 该项目将计算和比较标准化措施 预防艾滋病毒干预措施的成本效益和 各种干预措施中的性传播感染（STI）， 使用实际 HIV/STI 数据确定地理区域和目标人群 非洲、拉丁美洲和亚洲的干预项目。 性项目 选择进行评估的人员均与 AIDSCAP 项目相关，该项目受到资助 由美国国际开发署制定，包括：(1) 多米尼加共和国对性工作者的全面干预，(2)a 针对男男性行为者的同伴教育和咨询干预 多米尼加共和国，(3) 性传播疾病和同伴教育干预 坦桑尼亚的工人，(4) 农村地区的社区预防计划 坦桑尼亚，(5) 泰国工厂工人的干预，以及 (6) 针对曼谷贫困妇女的全面艾滋病毒和性传播疾病干预措施， 泰国。 全面、标准化的行为评价数据 适用于所有站点，并且成本数据将在初始时收集 项目的阶段。 类似未暴露的回顾性控制数据 还将对每个干预地点的人口进行汇编和分析。 主要结果是避免每个艾滋病毒病例的折扣成本， 以及每次干预的每个质量调整生命年 (QALY) 的成本。 该项目还将有助于培养申请人的技能和经验 进行建模和健康经济分析。

项目成果

Cost-effectiveness of environmental-structural communication interventions for HIV prevention in the female sex industry in the Dominican Republic.

多米尼加共和国女性性行业艾滋病毒预防的环境结构沟通干预措施的成本效益。

• DOI: 10.1080/10810730600974829
• 发表时间: 2006
• 期刊: Journal of health communication
• 影响因子: 4.4
• 作者: Sweat,Michael;Kerrigan,Deanna;Moreno,Luis;Rosario,Santo;Gomez,Bayardo;Jerez,Hector;Weiss,Ellen;Barrington,Clare
• 通讯作者: Barrington,Clare