DIGITAL HAND ATLAS IN ASSESSMENT OF SKELETAL DEVELOPMENT

说明(改编自摘要)： 骨龄评估是儿科患者经常进行的一种程序。 来评估他们的成长。它是诊断和治疗的一个重要步骤。 内分泌紊乱的管理，代谢和疾病的诊断评估 生长异常，各种综合征的成熟减速， 畸形和骨骼发育不良。它也被用于在 计划整形外科手术。一种简单的骨龄评估方法是 左腕X线片与小参考集的图谱匹配 由Greulich和Parle在 20世纪50年代。然而，这些参考X线片并不反映骨骼 当今欧洲、非洲、西班牙裔儿童和青少年的发展 或者是亚裔。因为美国的种族多样性和种族融合 各国正在增加，重新评估骨龄标准的使用情况 需要将其应用于不同种族的儿童。 这项提议是六年持续努力的第二阶段，并打算 完成具有大型标准集的数字手绘图谱的开发 四个不同种族儿童的正常手部和手腕图像，以及 基于Web的骨龄计算机辅助诊断系统的实现 评估。数字地图集，包括一大套1,120个参考文献 图像和计算机提取的骨骼对象和量化特征，删除 目前过时的格劳里希-派尔地图集的缺点和允许 骨龄评估要电脑化。这些图像收集自 平均分布正常新生儿至18岁，男性和女性， 欧洲人、非洲人、西班牙人和亚洲人后裔。生物多样性的数量特征 在Web服务器上提取患者被检查的手图像，然后进行比较 用阿特拉斯数据库中的图案来评估骨龄。

DESCRIPTION (adapted from the Abstract): Bone age assessment is a procedure frequently performed on pediatric patients to evaluate their growth. It is an important procedure in the diagnosis and management of endocrine disorders, diagnostic evaluation of metabolic and growth abnormalities, deceleration of maturation in a variety of syndromes, malformations, and bone dysplasias. It is also used for consultation in planning orthopedic procedures. A simple method for bone age assessment is atlas matching by a left-hand wrist radiograph against a small reference set of atlas patterns of normal standards developed by Greulich and Pyle in the 1950s. However, these reference radiographs do not reflect skeletal development in children and adolescents of today's European, African, Hispanic or Asian descent. Because racial diversity and racial mixing in the United States are increasing, reevaluation of the use of skeletal age standards when applied to children of diverse ethnicity is needed. This proposal is the second phase of a six-year continuing effort and intends to complete the development of a digital hand atlas with a large standard set of normal hand and wrist images of children of four diverse ethnic groups, and to implement a Web-based computer-aided diagnostic system for bone age assessment. The digital atlas, comprising a large set of 1,120 reference images and computer-extracted bone objects and quantitative features, removes the disadvantages of the currently out-of-date Greulich-Pyle atlas and allows the bone age assessment to be computerized. These images are collected from evenly distributed normal newborn to 18 years of age, male and female, European, African, Hispanic, and Asian descent. Quantitative features on a patient examined hand image are extracted on the Web server and then compared with patterns from the atlas database to assess the bone age.