Soft-Hard Tissue Engineering for Synthetic Bone Manufacturing using Ultrafast Lasers

目前世界上用于替代受损骨组织的生物相容骨材料严重短缺。博士学位的主题将集中在一种使用超快激光和先进生物材料的合成骨材料工程的新方法。多学科的研究将集中在钙磷矿物与胶原、蛋白质和生长因子基因的顺序沉积上。通过工程硬(矿物)-软(胶原蛋白、蛋白质、生长因子)制造骨材料的方法还将检查合成骨制造的微观力学、结构和生物相容性。制造工程还将辅之以细胞活性测试方面的培训。在该项目中，学生将接受激光加工、表征、细胞活力和微观机械等核心研究领域的培训。这位博士生还将通过与临床医生合作获得一些经验。

There is a huge shortage of bio-compatible bone materials in the world for replacing damaged bone tissue. The PhD topic will focus on a novel method for synthetic bone materials engineering using ultrafast lasers and advanced bio-materials. The multidisciplinary research will focus on the sequential deposition of calcium phosphate minerals with collagen, and protein and growth factor gene. The method of bone materials fabrication by engineering hard (mineral)-soft (collagen, protein, growth factor) will also examine micro-mechanics, structure, and bio-compatibility for synthetic bone manufacturing. The manufacturing engineering will also be supplemented by training in cell viability tests. In the project the student will be trained in the core areas of research in laser processing, characterisation, cell viability and micro-mechanics. The PhD student will also gain some experience by working with clinicians.