EFFECT OF ENALAPRIL ON URINARY CITRATE EXCRETION

依那普利对柠檬酸盐尿排泄的影响

• 批准号: 6414536
• 负责人: KHASHAYAR SAKHAEE
• 金额: $ 32.14万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-12-01 至 2001-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6414536
• 关键词: ACE inhibitors; citrates; clinical research; disease /disorder proneness /risk; enalapril; excretion; human subject; nephrolithiasis; urinalysis

This study will determine if angiotensin converting enzyme inhibitors in humans exert a significant effect on urinary citrate excretion. Because these drugs are commonly used to treat many renal and cardiovascular diseases, knowledge of their effect on urinary citrate excretion would be important before prescribing them to persons at risk for developing kidney stones.

这项研究将确定血管紧张素转换酶抑制剂是否 在人体中对尿柠檬酸盐排泄有显着影响。 因为这些药物通常用于治疗许多肾病和 心血管疾病及其对尿柠檬酸盐影响的知识 在给高危人群开药之前，排泄很重要 用于形成肾结石。