INTEGRATED ASSESSMENT OF CALCIUM METABOLISM

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This long-standing generic mineral metabolism protocol has proven to be continually useful in assessing unusual disorders of mineral metabolism. Its' utilization was particularly noteworthy in assessing the factors affecting calcium absorbability, food-calcium interaction, effect of lithotripsy on stone- forming risks, changes in calcium metabolism ensuing from GnRH agonist therapy and pathogenetic background in unusual cases of hypercalcemia, osteoporosis, and miscellaneous bone diseases.