CLASSIFICATION OF PROTEIN STRUCTURES

如何客观地对蛋白质结构进行分类和分类 明确的方式是蛋白质结构中的一个长期存在的问题 认可。我们正在开发一种图论方法来给出一个 严格解析不同可能的链折叠为构象 分类学。具体地说，我们正在处理二级结构单元 (例如，螺旋线)作为平面图上的顶点。现有的图形 然后，理论对该图进行了严格的数学描述。 这样的分类方案正被用来预测蛋白质 给定序列的结构。我们使用计算机上的资源 图形实验室来可视化我们的结果。

How to classify proteins structures in an objective and unambiguous way is a long-standing problem in protein structure recognitions. We are developing a graph theory approach to give a rigorous parsing of different possible chain folds into conformational taxonomies. Specifically, we are treating secondary structural unit (e.g., a helix) as a vertex on a planar graph. The existing graph theory then gives a rigorous mathematical description of the graph. Such a classification scheme is being used to predict protein structures for given sequences. We use the resources at the Computer Graphics Laboratory to visualize our results.