Effects of nevogenesis susceptibility genes and phenotypic correlation with dermoscopic characteristics of nevi

新生易感基因的影响及表型与痣皮肤镜特征的相关性

• 批准号: nhmrc : 1004999
• 负责人: A/Pr Richard Sturm
• 金额: $ 36.95万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/effects-nevogenesis-susceptibility-characteristics-nevi/109083
• 关键词: Effects; nevogenesis; susceptibility; genes; phenotypic

Melanoma is a form of skin cancer that arises from the cells that produce pigment and is a major public health issue in Australia. We will examine the relationship between the form, structure and colour of existing types of moles and their subsequent risk of developing into melanoma. This will be the first study to combine dermoscopy, a non-invasive examination technique, with DNA tests of the genes that determine skin, hair and eye colour, aiding in the early prediction and diagnosis of skin cancer.

黑色素瘤是一种皮肤癌，由产生色素的细胞引起，是澳大利亚的一个主要公共卫生问题。我们将检查现有类型痣的形式、结构和颜色与其随后发展为黑色素瘤的风险之间的关系。这将是第一项将皮肤镜检查（一种非侵入性检查技术）与决定皮肤、头发和眼睛颜色的基因 DNA 测试相结合的研究，有助于皮肤癌的早期预测和诊断。