Human pigmentation genetics, melanocyte biology and skin cancer

人类色素沉着遗传学、黑素细胞生物学和皮肤癌

• 批准号: nhmrc : 1043187
• 负责人: A/Pr Richard Sturm
• 金额: $ 45.79万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/human-pigmentation-genetics-skin-cancer/111556
• 关键词: Human; pigmentation; genetics; melanocyte; biology

The fellowship application by A/Prof Sturm is to support his research into the biology of human skin, hair and eye colour, and the process of melanoma formation. His pivotal discoveries into the genetic basis of pigmentation and its regulation has provided an understanding of these physical traits and the associated genotypic risk factors for skin cancer development. The genes that determine an individual's skin phototype and the mechanisms involved in the tanning response after UV-exposure of the skin are actively being investigated.

斯特姆教授申请的奖学金是为了支持他对人类皮肤、头发和眼睛颜色的生物学研究，以及黑色素瘤形成过程的研究。他在色素沉着及其调控的遗传基础上的关键发现，提供了对这些物理特征和皮肤癌发展相关基因型风险因素的理解。决定个体皮肤光型的基因以及皮肤暴露于紫外线后晒黑反应的机制正在积极研究中。