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F0F1 ATPASE STRUCTURAL STUDIES

F0F1 ATPASE STRUCTURAL STUDIES
F0F1 ATP酶结构研究
批准号:
6504527
负责人:
PETER L PEDERSEN
金额:
$13.47万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2000
资助国家:
美国
项目状态:
已结题
起止时间:
2000-12-01 至 2001-11-30

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中文摘要
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英文摘要
The ATP synthase from mitochondria of animal cells is an important enzyme which couples proton translocation to ATP synthesis, to provide chemical energy needed for many biological processes. It consists of F1 (a soluble domain with 5 subunit types of a total mass of 370 kD), a stalk and F0 (a membrane domain with at least three subunit types). The x ray crystallographic structure for the F1 has been determined to 2.8  but the structure of the rest of the molecule is still unknown. We have carried out preliminary experiments to image the entire enzyme with the hope that we can define the overall organization of the three components of this large enzyme.
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REGULATION OF MITOCHONDRIAL ATP SYNTHASE
  • 批准号:
    7114082
  • 项目类别:
  • 资助金额:
    $39.98万
  • 财政年份:
    2005
  • 负责人:
    PETER L PEDERSEN
  • 依托单位:
MITOCHONDRIAL ATP SYNTHASOME
  • 批准号:
    7181086
  • 项目类别:
  • 资助金额:
    $3.69万
  • 财政年份:
    2004
  • 负责人:
    PETER L PEDERSEN
  • 依托单位:
MITOCHONDRIAL ATP SYNTHASOME
  • 批准号:
    6980395
  • 项目类别:
  • 资助金额:
    $2.17万
  • 财政年份:
    2003
  • 负责人:
    PETER L PEDERSEN
  • 依托单位:
F0F1 ATPASE STRUCTURAL STUDIES
  • 批准号:
    6611287
  • 项目类别:
  • 资助金额:
    $13.47万
  • 财政年份:
    2001
  • 负责人:
    PETER L PEDERSEN
  • 依托单位:
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