Sub-millimeter Nuclear Medicine Imaging at Low Energies

描述(由申请人提供)： 拟议的研究将解决体内对更高分辨率的需求 通过将辐射探测器的最新创新结合在一起进行成像， 多针孔成像光圈和重建算法 超高分辨率层析成像系统的研制该设备 将使用硅双面条带探测器(DSDs)，其固有的 位置分辨率将至少比 用于核医学的常规闪烁相机。硅片 所使用的探测器非常适合于检测低电平。 1251年和1231年衰变产生的能量(27-35keV)光子。有能力 广泛的分子碘化使这样的体系适用于许多 用途，特别是在小动物成像领域。

DESCRIPTION (provided by applicant): The proposed research will address the need for higher resolution in vivo imaging by bringing together recent innovations in radiation detectors, multiple-pinhole imaging apertures, and reconstruction algorithms in the development of an ultrahigh-resolution tomographic imaging system. The device will utilize silicon double-sided strip detectors (DSSDs) whose intrinsic position resolution will be at least an order of magnitude better than conventional scintillation cameras used in nuclear medicine. The silicon detectors that are to be used are well-suited to the detection of the low- energy (27-35 keV) photons from the decay of 1251 and 1231. The ability to iodinate a wide range of molecules makes such a system applicable to many uses, particularly in the field of small-animal imaging.