PET System for Preclinical Research

描述(由申请者提供)：这份共享仪器赠款提案是为了购买一台专用的小动物PET扫描仪。NIH资助的需要该系统的研究项目主要旨在开发新的分子成像剂，并验证现有的放射性示踪剂，用于研究基本的生物过程和评估治疗干预的影响。该系统将设在小动物成像中心(CSAI)，与代表主要体内成像方式(超声波、生物发光/荧光、SPECT、MRI和MRS)的系统一起安装。CSAI是该大学的核心机构，是范德比尔特大学成像科学研究所的一部分。PET系统将由经验丰富的成像科学家团队和高素质的支持人员提供支持。它也将是由我们在癌症成像方面的机构培训拨款支持的博士后和博士后学员以及我们在成像科学方面的其他学员的关键资源。

DESCRIPTION (provided by applicant): This shared instrumentation grant proposal is for the purchase of a dedicated small-animal PET scanner. The NIH-funded research projects that require this system are aimed primarily at developing new molecular imaging agents and validating existing radiotracers for the investigation of fundamental biological processes and the assessment of the impact of therapeutic interventions. The system will be located in the Center for Small Animal Imaging (CSAI) alongside systems representing the major in vivo imaging modalities (ultrasound, bioluminescence/fluorescence, SPECT, MRI and MRS). The CSAI functions as a Core Facility for the university and operates as part of the Vanderbilt University Institute of Imaging Science. The PET system will be supported by an experienced group of imaging scientists and a highly qualified support staff. It also will be a key resource for predoctoral and postdoctoral trainees supported by our institutional training grants in cancer imaging as well as our other trainees in imaging science.