CBW Protective Clothing for Civilian Protection

用于平民保护的 CBW 防护服

• 批准号: 6549243
• 负责人: SHANTHA s SARANGAPANI
• 金额: $ 16.83万
• 依托单位: INNOVATIVE CHEMICAL/ENVIRONMENTAL TECH
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-20 至 2004-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6549243
• 关键词: Bacillus subtilis; aerosols; anthrax; artificial membranes; biohazard control; bioterrorism /chemical warfare; consumer product; gas poisoning; hazardous substances; mustard compounds; nonbiomedical equipment; safety equipment; skin irritation /irritant; spores; technology /technique development

DESCRIPTION (provided by applicant): The Phase I work has demonstrated the fabrication of a thin, strong, lightweight composite material that could be scaled up from the laboratory to industrial pilot quantities. The phase I material shows no breakthrough flux of mustard and nerve agents (HD and GB) (actual chemical warfare agents) for over 48 hrs, which exceeds the current 8hrs criteria for suits, as verified by an Army certified laboratory. The composition presents a powerful self-decontaminating, triple defense concept- Chemical agent deactivation, barrier effect and biocidal effect. In addition the material is moisture vapor permeable (breathable) but not air permeable. The biocidal activities of the composites against Anthrax surrogate Bacillus var. niger spores and Anthrax spores were firmly established. Typically 4-5 log reductions (total kill) were noted when the samples were exposed to Anthrax, Bacillus spores and other pathogens. The capacity to kill over 70 million anthrax spores! 50 cm2 of the phase I material was recorded. The phase II would concentrate on optimizing the assembly of the membrane to an outer shell fabric. The optimization of the thickness, composition, and production parameters will be done. Quantitative kill kinetic curves for aerosolized Anthrax spores and certain viral and bacterial species will be established. The deactivation of chemical agent kinetics and resistance to aerosol penetration will be demonstrated. A reputable team of experts from the Army laboratories and textile industry has been assembled to carry out all the qualifying tests for such a material. The protection factor offered by these suits will be characterized by the Army materials laboratory. Commercial partners have been identified. PROPOSED COMMERCIAL APPLICATIONS: The market size for the protective clothing for civilians, police, medical personnel and fire fighters for domestic preparedness is expected to be 2 billion dollars by year 2004. ICET's market share is estimated to be about 200 million dollars five years after commercial entry.

描述（由申请人提供）：第一阶段的工作证明了可以从实验室到工业飞行员数量的薄质，强，轻巧的复合材料的制造。第一阶段的材料显示，芥末和神经剂（HD和GB）（实际的化学战剂）的突破性不超过48小时，这超过了当前的8小时套件标准，该标准由陆军认证的实验室验证。 该构图提出了强大的自我抗衡，三重防御概念 - 化学剂失活，障碍效应和杀生物效应。此外，材料是水分蒸气可渗透（透气），但不可渗透。复合材料对炭疽替代芽孢杆菌的杀菌活性。尼日尔孢子和炭疽孢子牢固地确定。通常，当样品暴露于炭疽，芽孢杆菌和其他病原体时，通常会注意到4-5个对数减少（总杀死）。杀死超过7,000万个炭疽孢子的能力！记录了I期材料的50 cm2。 II期将集中于优化膜的组装到外壳织物。将完成厚度，成分和生产参数的优化。将建立用于雾化的炭疽孢子和某些病毒和细菌物种的定量杀死动力学曲线。将证明化学剂动力学的失活和对气溶胶渗透的耐药性。来自陆军实验室和纺织行业的一支著名的专家团队已经组装，以对这种材料进行所有合格测试。这些西装提供的保护因素将以陆军材料实验室为特征。已经确定了商业合作伙伴。 拟议的商业应用： 预计到2004年，预计平民，警察，医务人员和消防员的防护服的市场规模预计将为20亿美元。据估计，商业投入五年后，ICET的市场份额约为2亿美元。