CBW Protective Clothing for Civilian Protection

用于平民保护的 CBW 防护服

• 批准号: 6549243
• 负责人: SHANTHA s SARANGAPANI
• 金额: $ 16.83万
• 依托单位: INNOVATIVE CHEMICAL/ENVIRONMENTAL TECH
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-20 至 2004-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6549243
• 关键词: Bacillus subtilis; aerosols; anthrax; artificial membranes; biohazard control; bioterrorism /chemical warfare; consumer product; gas poisoning; hazardous substances; mustard compounds; nonbiomedical equipment; safety equipment; skin irritation /irritant; spores; technology /technique development

DESCRIPTION (provided by applicant): The Phase I work has demonstrated the fabrication of a thin, strong, lightweight composite material that could be scaled up from the laboratory to industrial pilot quantities. The phase I material shows no breakthrough flux of mustard and nerve agents (HD and GB) (actual chemical warfare agents) for over 48 hrs, which exceeds the current 8hrs criteria for suits, as verified by an Army certified laboratory. The composition presents a powerful self-decontaminating, triple defense concept- Chemical agent deactivation, barrier effect and biocidal effect. In addition the material is moisture vapor permeable (breathable) but not air permeable. The biocidal activities of the composites against Anthrax surrogate Bacillus var. niger spores and Anthrax spores were firmly established. Typically 4-5 log reductions (total kill) were noted when the samples were exposed to Anthrax, Bacillus spores and other pathogens. The capacity to kill over 70 million anthrax spores! 50 cm2 of the phase I material was recorded. The phase II would concentrate on optimizing the assembly of the membrane to an outer shell fabric. The optimization of the thickness, composition, and production parameters will be done. Quantitative kill kinetic curves for aerosolized Anthrax spores and certain viral and bacterial species will be established. The deactivation of chemical agent kinetics and resistance to aerosol penetration will be demonstrated. A reputable team of experts from the Army laboratories and textile industry has been assembled to carry out all the qualifying tests for such a material. The protection factor offered by these suits will be characterized by the Army materials laboratory. Commercial partners have been identified. PROPOSED COMMERCIAL APPLICATIONS: The market size for the protective clothing for civilians, police, medical personnel and fire fighters for domestic preparedness is expected to be 2 billion dollars by year 2004. ICET's market share is estimated to be about 200 million dollars five years after commercial entry.

描述(由申请人提供)：第一阶段的工作展示了一种薄、强、轻的复合材料的制造，这种材料可以从实验室扩大到工业中试数量。第一阶段材料显示，超过48小时没有芥末和神经毒剂(HD和GB)(实际的化学战剂)的突破通量，这超过了经陆军认证的实验室验证的当前8小时的西装标准。 该组合物呈现出强大的自去污、三防概念--化学制剂失活、屏障作用和生物杀灭作用。此外，这种材料具有透湿性(透气性)，但不透气性。研究了这些化合物对炭疽杆菌替代变种的杀灭活性。尼日尔孢子和炭疽孢子被牢固地建立起来。当样本暴露在炭疽、芽孢杆菌和其他病原体中时，通常记录到4-5个对数减少(总杀灭)。第一阶段材料的杀灭能力超过7000万个炭疽孢子！50平方厘米被记录下来。 第二阶段将集中于优化膜与外壳织物的组装。将对厚度、成分和生产参数进行优化。将建立气雾化炭疽孢子和某些病毒和细菌的定量杀灭动力学曲线。将演示化学试剂动力学的失活和对气溶胶渗透的抵抗力。来自陆军实验室和纺织行业的一支声誉卓著的专家团队已经被召集起来，对这种材料进行所有合格的测试。这些防护服提供的保护因素将由陆军材料实验室来确定。已经确定了商业合作伙伴。 建议的商业应用： 预计到2004年，民用、警察、医务人员和消防员的国内防护服的市场规模将达到20亿美元。ICET进入商业市场五年后，其市场份额估计约为2亿美元。