CENTER FOR MOLECULAR, DEVELOPMENTAL AND BEHAVIORL NEURO

分子、发育和行为神经中心

• 批准号: 6529890
• 负责人: CONCHITA ZUAZAGA
• 金额: $ 151.97万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-30 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6529890
• 关键词: behavioral /social science research tag; developmental neurobiology; ethology; hormone regulation /control mechanism

In response to RNA #RR-00-003, entitled Centers of Biomedical Research Excellence (COBRE), the University of Puerto Rico (UPR) submits this multi-disciplinary application entitled Center for Molecular Developmental and Behavioral Neuroscience. This proposal is part of a UPR systemwide initiative to move the institution into the Research I category according to the Carnegie Classification. The University is nurturing and promoting the formation of these systemwide efforts under its initiative to create Multi-campus and Multi-disciplinary Research Institutes. The COBRE proposal could serve as the foundation for the development of one of these institutes. The prime objectives of this proposal are to: 1) create a competitive research center in neuroscience that will optimize the capacity of the UPR system to compete nationally, 2) develop young scientists into competitive RO1 researchers under the leadership of a Center Director and the scientific guidance of an External Advisory Committee; and 3) expand the capacity of a neuroscience research in Puerto Rico. The goals of the proposed collaborative research projects are to advance the scientific understanding of the molecular mechanisms underlying neuronal injury, emotional memory, cocaine- seeking behavior, and the expression of maternal behavior. These goals and objectives will be achieved by: 1) hiring an established researcher in the field of neuroscience to provide leadership and guidance to the Center; 2) hiring three additional competitive researchers to develop a cadre of neuroscience competency in PR; and 3) providing a supportive and nurturing environment (with the full backing of the administration) for the developing young faculty. The Advisory Committee, chaired by Dr. Edward A. Kravitz, George Packer Berry Professor of Neurobiology at the Harvard School of Medicine, will provide scientific guidance for the development of a strong thrust in neuroscience at UPR and the development of RO1 researchers. The University will provide the resources ($2.5 M in direct match funds plus four professional lines) for recruiting and hiring the Permanent Center Director and three new scientists and provide them the necessary startup funds to help them establish their laboratories.

为了响应RNA＃RR-00-003，题为《生物医学研究卓越中心》（COBRE），波多黎各大学（UPR）提交了这一题为《分子发育和行为神经科学中心》的多学科应用。该提案是根据卡内基分类将机构转移到研究I类别的UPR系统范围内的一部分。该大学正在培养和促进这些系统范围内的努力，以创建多校园和多学科研究机构。毛绒提案可以作为开发这些机构之一的基础。该提案的主要目标是：1）在神经科学中创建一个竞争性的研究中心，该中心将优化UPR系统在全国范围内竞争的能力，2）在中心主任的领导下，将年轻科学家培养为竞争性的RO1研究人员，并在外部咨询委员会的科学指导下； 3）扩大波多黎各神经科学研究的能力。拟议的协作研究项目的目标是提高对神经元损伤，情绪记忆，可卡因寻求行为和孕产妇行为的分子机制的科学理解。这些目标和目标将通过：1）在神经科学领域雇用一名既定研究人员，以向中心提供领导和指导； 2）雇用另外三名竞争研究人员来发展PR的神经科学能力； 3）为发展中的年轻教师提供一个支持和培养的环境（并得到政府的全部支持）。哈佛医学学院乔治·帕克·贝里（George Packer Berry）神经生物学教授爱德华·克拉维兹（Edward A.该大学将提供资源（直接匹配资金以及四个专业线路），以招募和雇用常任中心主任和三名新科学家，并为他们提供必要的启动资金，以帮助他们建立实验室。