MASTER OF SCIENCE DEGREE IN CLINICAL INVESTIGATION

临床研究理学硕士学位

• 批准号: 6527052
• 负责人: MICHAEL J. LICHTENSTEIN
• 金额: $ 19.95万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-30 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6527052
• 关键词: Hispanic Americans; clinical research; curriculum; education evaluation /planning; ethics; experimental designs; health science research; minority health professional; postgraduate education; statistics /biometry; technical writing

In recent years, it has become obvious that there is a special need for investigators trained in clinical research. The biotechnology revolution has provided many possible avenues to improve 0ult, lives, but these advances require expertise in patient- oriented research for them to benefit mankind. We plan to use the resources we have in San Antonio to provide an innovative training program in clinical research to train young scientists, physicians, dentists, nurses and allied health professionals for successful careers in clinical investigation. We plan to do this through a new Master of Science Degree in Clinical Investigation (MSCI). The 'laboratory' for our trainees will be the General Clinical Research Center, which is an NIH-funded General Clinical Research Center located in one of our teaching hospitals. A special goal will be to increase the number of ethnically diverse students, particularly Mexican-Americans and other Hispanic groups, who will be trained in the conduct of clinical research. Once trained, graduates of this program will be expert in the design and conduct of patient-oriented research studies involving direct interactions between investigators and human subjects. The preceptors for this training program are faculty members with active programs in clinical research, molecular biology, protein chemistry and cell biology, and who have proven expertise in running successful research programs and in obtaining extramural grant support. Since MDs lack the formal didactic training characteristic of many Phi) programs, we have established an organized didactic program designed to prepare our trainees to function as future independent clinical researchers. Candidates enrolling in the MSCI program will complete a mentored research project over two years while participating in a highly integrated set of six didactic courses. The courses include: (a) Research Methodology (3 semesters); (b)Biostatistics (3 semesters); (c) Ethical Conduct of Research (I semester); (d) Integration of Molecular Biology into Clinical Research (l semester); (e) Data management, Quality Control, and Regulatory Issues (l semester); and (f) Scientific Writing (l semester). Our goal is to prepare investigators skilled in the conduct of outstanding clinical research in culturally diverse settings. MSCI program effectiveness will be ascertained by monitoring a cohesive set of five primary outcomes. These outcomes are: (a) the number of ethnically diverse trainees enrolled; (b) the number of enrolled students who attain their degrees; (c) the number of scientific peer-reviewed publications resulting from MSCI research projects; (d) the career paths chosen by the MSCI graduates; and (e) the success rate at which MSCI graduates compete for career development and research awards.

近年来，很明显，对受过临床研究培训的研究人员有特殊的需求。生物技术革命提供了许多可能的途径来改善人们的生活，但这些进步需要以患者为导向的研究方面的专业知识，才能造福人类。我们计划利用我们在圣安东尼奥拥有的资源，提供临床研究方面的创新培训计划，以培训年轻的科学家、医生、牙医、护士和专职医疗专业人员，使他们能够在临床研究领域取得成功。我们计划通过一个新的临床调查理学硕士学位(MSCI)来做到这一点。我们受训人员的“实验室”将是普通临床研究中心，这是一个由美国国立卫生研究院资助的普通临床研究中心，位于我们的一家教学医院。一个特殊的目标将是增加不同种族的学生的数量，特别是墨西哥裔美国人和其他拉美裔群体，他们将接受临床研究方面的培训。一旦接受培训，该项目的毕业生将成为设计和实施以患者为中心的研究研究的专家，这些研究涉及研究人员和人类受试者之间的直接互动。这一培训计划的导师是在临床研究、分子生物学、蛋白质化学和细胞生物学方面拥有活跃计划的教职员工，他们在成功实施研究计划和获得校外资助方面拥有公认的专业知识。由于医学博士缺乏许多Phi)计划所特有的正规教学培训，我们建立了一个有组织的教学计划，旨在为我们的受训人员做好准备，使其成为未来的独立临床研究人员。参加MSCI项目的考生将在两年内完成一项有指导的研究项目，同时参加一套高度整合的六门教学课程。课程包括：(A)研究方法论(3学期)；(B)生物统计学(3学期)；(C)研究伦理(第一学期)；(D)分子生物学与临床研究的整合(L学期)；(E)数据管理、质量控制和监管问题(L学期)；(F)科学写作(L学期)。我们的目标是培养在不同文化背景下熟练开展杰出临床研究的研究人员。MSCI计划的有效性将通过监测一套连贯的五项主要成果来确定。这些结果是：(A)不同种族的学员人数；(B)获得学位的在校学生人数；(C)MSCI研究项目产生的经同行评议的科学出版物数量；(D)MSCI毕业生选择的职业道路；以及(E)MSCI毕业生竞争职业发展和研究奖项的成功率。