MASTER OF SCIENCE DEGREE IN CLINICAL INVESTIGATION

临床研究理学硕士学位

• 批准号: 6527052
• 负责人: MICHAEL J. LICHTENSTEIN
• 金额: $ 19.95万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-30 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6527052
• 关键词: Hispanic Americans; clinical research; curriculum; education evaluation /planning; ethics; experimental designs; health science research; minority health professional; postgraduate education; statistics /biometry; technical writing

In recent years, it has become obvious that there is a special need for investigators trained in clinical research. The biotechnology revolution has provided many possible avenues to improve 0ult, lives, but these advances require expertise in patient- oriented research for them to benefit mankind. We plan to use the resources we have in San Antonio to provide an innovative training program in clinical research to train young scientists, physicians, dentists, nurses and allied health professionals for successful careers in clinical investigation. We plan to do this through a new Master of Science Degree in Clinical Investigation (MSCI). The 'laboratory' for our trainees will be the General Clinical Research Center, which is an NIH-funded General Clinical Research Center located in one of our teaching hospitals. A special goal will be to increase the number of ethnically diverse students, particularly Mexican-Americans and other Hispanic groups, who will be trained in the conduct of clinical research. Once trained, graduates of this program will be expert in the design and conduct of patient-oriented research studies involving direct interactions between investigators and human subjects. The preceptors for this training program are faculty members with active programs in clinical research, molecular biology, protein chemistry and cell biology, and who have proven expertise in running successful research programs and in obtaining extramural grant support. Since MDs lack the formal didactic training characteristic of many Phi) programs, we have established an organized didactic program designed to prepare our trainees to function as future independent clinical researchers. Candidates enrolling in the MSCI program will complete a mentored research project over two years while participating in a highly integrated set of six didactic courses. The courses include: (a) Research Methodology (3 semesters); (b)Biostatistics (3 semesters); (c) Ethical Conduct of Research (I semester); (d) Integration of Molecular Biology into Clinical Research (l semester); (e) Data management, Quality Control, and Regulatory Issues (l semester); and (f) Scientific Writing (l semester). Our goal is to prepare investigators skilled in the conduct of outstanding clinical research in culturally diverse settings. MSCI program effectiveness will be ascertained by monitoring a cohesive set of five primary outcomes. These outcomes are: (a) the number of ethnically diverse trainees enrolled; (b) the number of enrolled students who attain their degrees; (c) the number of scientific peer-reviewed publications resulting from MSCI research projects; (d) the career paths chosen by the MSCI graduates; and (e) the success rate at which MSCI graduates compete for career development and research awards.

近年来，明显需要接受过临床研究培训的研究者。生物技术革命为改善人类生活提供了许多可能的途径，但这些进步需要以患者为导向的研究方面的专业知识，才能造福人类。我们计划利用我们在圣安东尼奥的资源提供临床研究方面的创新培训计划，以培训年轻科学家、医生、牙医、护士和专职医疗专业人员，以在临床研究领域取得成功的职业生涯。我们计划通过新的临床研究理学硕士学位（MSCI）来实现这一目标。 我们学员的“实验室”将是普通临床研究中心，这是一个由 NIH 资助的普通临床研究中心，位于我们的一所教学医院内。一个特殊的目标是增加不同种族学生的数量，特别是墨西哥裔美国人和其他西班牙裔群体，他们将接受临床研究方面的培训。经过培训后，该项目的毕业生将成为设计和进行以患者为导向的研究的专家，这些研究涉及研究人员与人类受试者之间的直接互动。该培训项目的导师是在临床研究、分子生物学、蛋白质化学和细胞生物学领域积极开展项目的教员，他们在成功开展研究项目和获得校外资助支持方面拥有经过验证的专业知识。由于医学博士缺乏许多 Phi) 计划的正式教学培训特征，因此我们建立了一个有组织的教学计划，旨在帮助我们的学员做好未来独立临床研究人员的准备。参加 MSCI 计划的候选人将在两年内完成一个指导研究项目，同时参加一套高度综合的六门教学课程。课程包括： (a) 研究方法（3 个学期）； (b)生物统计学（3个学期）； (c) 研究的道德行为（第一学期）； (d) 将分子生物学纳入临床研究（一学期）； (e) 数据管理、质量控制和监管问题（一学期）； (f) 科学写作（一学期）。我们的目标是培养能够在不同文化背景下进行杰出临床研究的研究人员。 MSCI 计划的有效性将通过监测五个主要结果来确定。这些结果是： (a) 注册的不同种族学员的数量； (b) 获得学位的在校学生人数； (c) MSCI 研究项目产生的科学同行评审出版物的数量； (d) MSCI 毕业生选择的职业道路； (e) MSCI 毕业生竞争职业发展和研究奖项的成功率。