CORE--NEUROCHEMISTRY SERVICES

核心——神经化学服务

• 批准号: 6448235
• 负责人: MICHAEL J ZIGMOND
• 金额: $ 20.73万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-05-01 至 2003-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6448235
• 关键词: aminoacid analyzer; analytical chemistry; aromatic L aminoacid decarboxylase; biomedical facility; dopamine; enzyme activity; high performance liquid chromatography; neurochemistry; serotonin; tissue /organ preservation; tyrosine 3 monooxygenase

This Core provides neurochemical analyses for members of the Program Project. In particular it analyzes the dopamine (DA) content of tissue taken from 6-OHDA-treated animals as a means of quantifying the impact of the lesion. Other assays available include that for serotonin, tyrosine hydroxylase activity, and protein. Additional analytical procedures will be developed as necessary.

该核心提供神经化学分析的成员 计划项目。特别是，它分析了多巴胺(DA) 以6-OHDA处理动物的组织含量为指标 对损伤的影响进行量化。其他可用的检测方法 包括5-羟色胺、酪氨酸羟基酶活性和 蛋白。额外的分析方法将被开发为 这是必要的。