Signaling by Adhesion Receptors

粘附受体的信号传导

• 批准号: 6505454
• 负责人: Richard Assoian
• 金额: $ 2.2万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6505454
• 关键词: biological signal transduction; cell adhesion; cytoskeleton; guanosinetriphosphatases; meeting /conference /symposium; receptor; travel

DESCRIPTION (provided by applicant): This application is a request for funding of the second Gordon Research Conference on A "Signaling by Adhesion Receptors" to be held July 14-19, 2002 at Connecticut College, New London, CT. This meeting was founded because signaling by adhesion receptors had not received sufficient attention within the necessarily broader formats of meetings on cell adhesion or signaling. Additionally, most cells in vitro use multiple adhesion receptors simultaneously, yet the existing meetings on adhesion systems typically focus on one receptor in isolation. Indeed, this conference has rapidly become a unique forum for bringing together signaling laboratories working on different adhesion receptors. The scientific value of cross-fertilizing these related fields became apparent when the inaugural meeting readily attracted international leaders in adhesion receptor signaling, was heavily oversubscribed, and received an extremely positive rating by the participants. While the 2002 A "Signaling by Adhesion Receptors" meeting described here continues to highlight the interplay between signaling by distinct adhesion receptors, it also emphasizes the major roles that Rho family GTPases and the cytoskeleton play as effectors in adhesion receptor signaling. The speakers include the most active groups in the ECM/integrin, cadherin/catenin and Rho GTPase fields. Several short talks and posters will complement the principal lectures and are intended to draw attention to the work of young investigators. As with the last meeting, I anticipate that the 2002 Gordon Conference on Signaling by Adhesion Receptors will be attended by a diverse array of professionals: basic scientists, physician-scientists, researchers in industry, and editors from leading cell and molecular biology journals. There is a strong cancer relevance to the program, but important new findings relevant to development, differentiation, vascular biology, neurobiology, and aging will also be presented.

描述（由申请人提供）： 该申请是为2002年7月14日至19日在康涅狄格州康涅狄格州康涅狄格学院举行的第二次戈登研究会议的筹集资金。 这次会议之所以成立，是因为在粘附受体的信号传导中没有在细胞粘附或信号传导的更广泛的会议形式中得到足够的关注。 此外，大多数体外细胞同时使用多个粘附受体，但是有关粘附系统的现有会议通常集中在一个分离的一个受体上。 的确，该会议迅速成为一个独特的论坛，将信号实验室汇集在一起​​，从事不同的粘附受体。 当开幕会议很容易吸引国际领导人的粘附受体信号传导，大量超额订阅并获得参与者的极为积极的评级时，使用这些相关领域的科学价值变得显而易见。 虽然此处描述的2002年“通过粘附受体信号传导”会议继续强调通过不同粘附受体信号传导之间的相互作用，但它还强调了Rho家族GTPase和细胞骨架在粘附受体信号中的效应子的主要作用。 扬声器包括ECM/整合素，钙粘蛋白/catenin和Rho GTPase场中最活跃的组。 几次简短的会谈和海报将补充主要讲座，并旨在引起人们对年轻调查人员的工作的关注。 与上次会议一样，我预计将有一系列专业人士参加2002年的戈登信号会议：基础科学家，医师 - 科学家，行业研究人员以及领先的细胞和分子生物学期刊的编辑。 与该计划有很强的癌症，但还将介绍与发展，分化，血管生物学，神经生物学和衰老有关的重要新发现。