Mechanisms of Toxicity Gordon Conference

描述（由申请人提供） 毒性机制戈登研究会议（GRC）自1956年以来每半年举行一次。 1992年，会议重新聚焦于分子毒理学和对环境损害的不良反应的机制。 在其目前的形式，会议探讨生物控制和有毒物质接触的影响的基本问题。 2002年会议的主题包括：1）基因组学和蛋白质组学在毒理学中的应用; 2）作为毒性靶点的整合素、钙粘蛋白和连接蛋白; 3）细胞信号传导和细胞周期控制; 4）受体介导的毒性; 5）氧化还原调节的转录控制; 6）发育中生物体的分子毒理学; 7）毒性中的程序性细胞死亡;和8）对毒物的遗传易感性。 演讲者是各自领域的领导者，将提供一个令人兴奋的跨学科计划，旨在吸引广泛的毒理学家和生物医学科学家。 该计划包括国际公认的领导者和有才华的新调查人员。 为出席会议的初级研究人员分配了时间，以便他们在从摘要中选出的讲台上介绍自己的工作，并在海报会议上介绍自己的工作。 共同主席将担任每次会议的讨论领导人，并担任最后会议的主席。 通过这些方式，会议的组织旨在最大限度地提高参与度，并增加与会者和演讲者以及高级和初级研究人员，博士后研究员和学生之间的互动。 在过去的几年里，基于该计划的高质量和会议对毒理学科学的重要贡献，毒性机制GRC获得了NIEHS的资助。 尽管如此，会议组织者对研究科和过去与会者的投入作出了反应。 会议议程包括新主题，以及对前几年仍然是前沿问题的主题的持续更新。 新的工作人员作为主席和共同主席也大量参与。 因此，毒性机制GRC准备继续其作为分子毒理学的单一领先的小型会议的增长。

DESCRIPTION (provided by the applicant) The Mechanisms of Toxicity Gordon Research Conference (GRC) has been held biannually since 1956. In 1992, the conference refocused on molecular toxicology and mechanisms that underlie adverse responses to environmental insults. In its present form, the meeting explores basic questions in biological control and the impact of toxicant exposure. Topics to be covered in the 2002 conference include: I) Applications of Genomics and Proteomics to Toxicology; 2) Integrins, Cadherins, and Connexins as Toxicant Targets; 3) Cellular Signaling and Cell Cycle Control; 4) Receptor-Mediated Toxicity; 5) Redox-Regulated Transcriptional Control; 6) Molecular Toxicology in the Developing Organism; 7) Programmed Cell Death in Toxicity; and 8) Genetic Susceptibility to Toxicants. Speakers are leaders in their fields and will provide an exciting cross-disciplinary program designed to appeal to a broad range of Toxicologists and biomedical scientists. The program includes internationally recognized leaders and talented new investigators. Time is allotted for junior investigators attending the meeting to present their work in podium presentations selected from the abstracts and in poster sessions. Co-Chairs will serve as discussion leaders in each session and also as Chairs of the Late Breaking Sessions. In these ways, the meeting is organized to maximize participation and increase interactions among the attendees and speakers, as well as senior and junior investigators, postdoctoral fellows, and students. The Mechanisms of Toxicity GRC has received funding from NIEHS in past years based on the high quality of the program and the important contribution of the meeting to the science of Toxicology. Nonetheless, the conference organizers have been response to input from both Study Section and past participants. The agenda for the meeting includes new topics mixed with continued updates on topics from previous years that remain cutting edge issues. There also is substantial involvement of new personnel as Chairs and co-Chairs. Thus, the Mechanism of Toxicity GRC is poised to continue its growth as the single leading small conference on Molecular Toxicology.