Community Clinical Oncology Program

描述（由申请人提供）：四个传统儿科的合并 组成儿童肿瘤学小组 (COG) 的合作小组提出了 为北美所有儿童提供服务的独特机会。我们的目标是 扩大癌症创新临床和转化研究的机会 治疗、预防和控制并提高参与水平 由 CCOP/MBCCOP 执行 COG 的使命。该应用程序支持COG 作为治疗和预防/控制社区临床肿瘤学计划 (CCOP) 研究基地。 COG 将向 CCOP/MBCCOP 提供当前的 获得研究药物和特殊药物的治疗方案 集中参考实验室，从而促进高质量的癌症护理 对于在社区环境中接受治疗的儿童。已被置于高度优先地位 开发可在较小 COG 中可行的协议 机构，其中包括我们大多数附属的 CCOP。 COG将鼓励 CCOP调查员参与集团科学的各个方面 除了招募患者参加研究之外，还执行任务。 COG 将提供 对 CCOP 机构人员的持续培训和支持，包括 临床研究助理和肿瘤科护士，并将确保所有 CCOP 维持会员资格、应计费用和会员资格的高质量保证标准 机构绩效。癌症控制委员会 (CCC) 负责管理 COG癌症预防与控制研究计划。它的使命是改善 癌症儿童的护理质量和生存率，以确保 为传统上服务不足的群体提供最先进的癌症治疗 （包括少数民族和青少年/年轻人），并发展 假设驱动的儿童预防和控制研究。的 CCC 的成员多种多样，包括以下临床学科： 血液学/肿瘤学、外科、放射治疗、肿瘤护理等 传染病、儿科心脏病学和 肺病学；公共卫生学科，包括流行病学、卫生服务 研究和生物统计学；和心理学的行为研究人员， 社会学和社会工作。 COG 癌症控制研究包括评估 替代试验终点，例如与健康相关的生活质量和经济 措施；识别和预防治疗相关后遗症； 症状管理、疼痛控制和支持治疗；和社区肿瘤学 和外展。

DESCRIPTION (provided by applicant): The merger of the four legacy pediatric cooperative groups to form the Children?s Oncology Group (COG) presents a unique opportunity to serve all children in North America. Our goals are to expand access to innovative clinical and translational research for cancer treatment, prevention and control and to increase the level of participation by CCOPs/MBCCOPs in the mission of the COG. This application supports the COG as a treatment and prevention/control Community Clinical Oncology Program (CCOP) Research Base. The COG will make available to CCOPs/MBCCOPs current treatment protocols with access to investigational agents and special centralized reference laboratories, thus promoting high quality cancer care for children treated in community settings. A high priority has been placed on developing protocols that can be feasibly performed in smaller COG institutions, which include most of our affiliated CCOPs. COG will encourage CCOP investigators to participate in all aspects of the Group?s scientific mission in addition to enrolling patients on study. The COG will provide continuing training and support for CCOP institutional personnel including clinical research associates and oncology nurses, and will ensure that all CCOPs maintain high quality assurance standards for membership, accrual, and institutional performance. The Cancer Control Committee (CCC) administers the COG cancer prevention and control research program. Its mission is to improve the quality of care and survivorship for children with cancer, to ensure access to state-of-the-art cancer therapy for traditionally underserved groups (including minority and adolescent/young adult populations), and to develop hypothesis-driven prevention and control research for children. The membership of the CCC is diverse and includes the clinical disciplines of hematology/oncology, surgery, radiation therapy, oncology nursing, and other physician specialists for infectious diseases, pediatric cardiology and pulmonology; public health disciplines including epidemiology, health services research, and biostatistics; and behavioral researchers in psychology, sociology and social work. COG cancer control research includes assessment of alternate trial endpoints such as health-related quality-of-life and economic measures; the identification and prevention of treatment-related sequelae; symptom management, pain control and supportive care; and community oncology and outreach.