COG NCORP Research Base

描述(申请人提供)：儿童肿瘤学组织(COG)是世界上最大的儿童癌症研究组织，包括224个儿科癌症项目，其使命是通过科学发现和慈悲关怀来治疗和预防儿童和青少年癌症。GOG于2000年由四个遗留的儿科合作小组合并而成，COG社区临床肿瘤学计划(CCOP)研究基地于2002年获得资助。拟议的COG NCORP研究基地将支持25个社区站点和12个少数民族/服务不足的社区站点，是唯一专门针对儿童和青少年的研究基地。它将涵盖几乎全部的美国社区儿科肿瘤学。COG NCORP研究基地将提供在社区场所进行最先进的癌症治疗的途径，并在全国范围内促进癌症预防和控制、治疗后监测/生存和癌症护理提供方面的儿科研究。COG试验和实验室研究将转化为更有效的治疗方法，减少副作用。以社区为基础的儿科肿瘤学家和其他卫生专业人员对COG的研究任务至关重要。NCORP网站提供了一种评估社区环境中使用的高级治疗方法的方法。COG向NCORP地点提供最新的治疗方案，使其能够接触到研究试剂和专门的中央参考实验室，对NCORP人员进行持续培训和支持，提供质量保证基础设施、数据管理和统计支持，从而促进科学发现和对年轻人的高质量癌症护理。COG在阐明不同的医疗保健提供系统和特征对癌症结果的影响，并确定某些种族/民族和服务不足的群体(如青少年和年轻人)较差结果的决定因素方面具有独特的地位。这类研究将通过消除青年癌症治疗和后续护理方面的差距和提高效率来改善结果。

DESCRIPTION (provided by applicant): The Children's Oncology Group (COG) is the largest childhood cancer research organization in the world encompassing 224 pediatric cancer programs with a mission to cure and prevent childhood and adolescent cancer through scientific discovery and compassionate care. GOG was formed from the merger of four legacy pediatric cooperative groups in 2000 and the COG Community Clinical Oncology Program (CCOP) Research Base was funded in 2002. The proposed COG NCORP Research Base will support 25 Community Sites and 12 Minority/Underserved Community Sites and is the only research base exclusively dedicated to children and adolescents. It will encompass the near totality of U.S. community pediatric oncology. The COG NCORP Research Base will provide access to state-of-the-art cancer treatment at community sites and nationally promote pediatric research in cancer prevention and control, post-treatment surveillance/survivorship, and cancer care delivery. COG trials and laboratory research will translate into more effective treatments with reduced side effects. Community-based pediatric oncologists and other health professionals are pivotal to COG's research mission. NCORP sites provide a means to evaluate advanced treatments administered in community settings. The COG makes available to NCORP sites current treatment protocols with access to investigational agents and special centralized reference laboratories, continuing training and support for NCORP personnel, quality assurance infrastructure, data management and statistical support, thus promoting scientific discovery and high quality cancer care for young persons. The COG is uniquely positioned to elucidate the impact of different health care delivery systems and characteristics on cancer outcomes and identify determinants of poorer outcomes in certain race/ethnic and underserved groups such as adolescents and young adults. Such research will improve outcomes by eliminating disparities and improving efficiencies for the delivery of cancer therapy and follow-up care in young persons.