Transcriptome sequencing and functional characterisation of craniate non-visual sensory systems and their adaptation to diverse light environments

颅骨非视觉感觉系统的转录组测序和功能表征及其对不同光环境的适应

• 批准号: DP140102117
• 负责人: Dr Wayne Davies
• 金额: $ 26.57万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP140102117
• 关键词: Transcriptome; sequencing; functional; characterisation; craniate

Light detection (photoreception) is critical to species survival. It is not limited to vision, but also serves to set biological rhythms. In mammals, all photoreception is thought to occur solely through the eye, but in non-mammals many other tissues directly monitor light levels. However, the signalling cascades and functional roles of these non-visual pathways are largely unknown. This project will use high-throughput sequencing technologies and functional analyses to trace the origin and function of different irradiance detection systems in each main craniate class. By comparing species from diverse photic habitats, the influence of light as a substrate for adaptation will be investigated.

光探测（光感受）对物种生存至关重要。它不仅限于视觉，还可以设定生物节律。在哺乳动物中，所有的光感受都被认为是通过眼睛发生的，但在非哺乳动物中，许多其他组织直接监测光水平。然而，这些非视觉通路的信号级联和功能作用在很大程度上是未知的。本项目将使用高通量测序技术和功能分析来追踪每个主要颅类中不同辐照检测系统的起源和功能。通过比较来自不同光生境的物种，将研究光作为适应基质的影响。