Delaware Biomedical Research Infrastructure Network

描述(由申请人提供)：特拉华州Brin旨在扩大特拉华州在基础分子和细胞生物科学方面的现有能力和专业知识。主要目标是建立和管理高级和初级研究人员网络、共享仪器，以及针对BRIN合作伙伴机构的特定任务和增长领域量身定做的特殊培训计划，并通过这样做来增加NIH生物医学研究资金网络的竞争力。该网络包括特拉华州所有提供理科研究生、本科生和副学士学位的高等教育机构，每年总共为超过7.2万名学生提供服务。特拉华州BRIN将围绕四个研究领域组织--所有领域都得到了先进的生物信息学能力的支持。这四个领域是：蛋白质结构和功能；细胞和细胞外结构生物学；分子相互作用；基因组和代谢组织。特拉华州分部将在四个核心的框架内支持这些领域的研究：管理、生物信息学、集中研究仪器以及培训和指导。合作机构是特拉华大学(UD)、特拉华生物技术研究所(DBI)、特拉华州立大学(DSU)、一所历史悠久的黑人大学、特拉华技术与社区学院(DelTech)和卫斯理学院。通过这一补充申请，一个新的机构合作伙伴加入了特拉华州Brin，即CCHS。 特拉华州Brin的具体目标是：a)开发5个集中式研究仪器设施，向特拉华州Brin社区的所有成员提供培训和访问；b)为初级教员和年轻研究人员提供指导和培训，以提高NIH获奖率；获得参加区域和国家科学会议的旅行奖励；c)通过以下方式推进UD、DSU、DelTech、CCHS和卫斯理学院生物技术/生命科学的本科生和研究生培训方案：为研究生/本科生提供新的学位方案和暑期研究实习；d)实施和扩大复杂的生物信息学网络，该网络将：连接伙伴机构和Brin核心；开发数据库和服务器；开发软件工具；并举办生物信息学研讨会。

DESCRIPTION (provided by applicant): The Delaware BRIN is intended to expand current capabilities and expertise in basic molecular and cellular biosciences in Delaware. The main goal is to build and administer a network of senior and junior investigators, shared instrumentation, and special training programs tailored to the specific missions and growth areas of the BRIN partner institutions, and in so doing to increase the competitiveness within the network for NIH biomedical research funding. The network includes all the institutions of higher education in Delaware that offer graduate, undergraduate and associate degrees in the sciences, serving a total of over 72,000 students each year. The Delaware BRIN will be organized around four research areas -- all are supported by advanced bioinformatics capabilities. The four areas are: Protein Structure and Function; Cellular and Extracellular Structural Biology; Molecular Interactions; Genomic and Metabolic Organization. The Delaware BRIN will support research in these areas within the framework of four cores: Administration, Bioinformatics, Centralized Research Instrumentation, and Training and Mentoring. The partner institutions are the University of Delaware (UD), the Delaware Biotechnology Institute (DBI), Delaware State University (DSU), a historically black university, Delaware Technical and Community College (DelTech), and Wesley College. With this supplement application, a new institutional partner joins the Delaware BRIN, the CCHS. The specific aims of the Delaware BRIN are to: a) Develop five centralized research instrumentation facilities, with training and access available to all members of the Delaware BRIN community, b) Provide mentoring and training for junior faculty and young investigators to increase NIH award rates; travel awards to attend regional and national scientific meetings, c) Advance undergraduate and graduate training programs in biotechnology / life sciences at UD, DSU, DelTech, CCHS and Wesley College through: new degree programs and summer research internships for graduate/undergraduate students; d) Implement and expand a sophisticated bioinformatics network that will: link partner institutions and BRIN cores; develop databases and servers; develop software tools; and conduct bioinformatics workshops.