Delaware Biomedical Research Infrastructure Network

描述（由申请人提供）：特拉华州的BRIN旨在扩大特拉华州在基础分子和细胞生物科学方面的现有能力和专业知识。主要目标是建立和管理一个由高级和初级研究人员组成的网络，共享仪器，并根据BRIN合作机构的具体任务和增长领域量身定制特殊培训计划，从而提高NIH生物医学研究资金网络内的竞争力。该网络包括特拉华州所有提供研究生、本科和副学士学位的高等教育机构，每年为超过72,000名学生提供服务。特拉华州的BRIN将围绕四个研究领域进行组织，所有这些研究领域都有先进的生物信息学能力支持。这四个领域是：蛋白质结构和功能；细胞和细胞外结构生物学；分子相互作用;基因组和代谢组织。特拉华州的BRIN将在四个核心框架内支持这些领域的研究：管理、生物信息学、集中研究仪器以及培训和指导。合作机构是特拉华大学（UD），特拉华生物技术研究所（DBI），特拉华州立大学（DSU），一所历史悠久的黑人大学，特拉华技术和社区学院（DelTech）和韦斯利学院。有了这个补充申请，一个新的机构合作伙伴加入了特拉华州的BRIN， CCHS。

DESCRIPTION (provided by applicant): The Delaware BRIN is intended to expand current capabilities and expertise in basic molecular and cellular biosciences in Delaware. The main goal is to build and administer a network of senior and junior investigators, shared instrumentation, and special training programs tailored to the specific missions and growth areas of the BRIN partner institutions, and in so doing to increase the competitiveness within the network for NIH biomedical research funding. The network includes all the institutions of higher education in Delaware that offer graduate, undergraduate and associate degrees in the sciences, serving a total of over 72,000 students each year. The Delaware BRIN will be organized around four research areas -- all are supported by advanced bioinformatics capabilities. The four areas are: Protein Structure and Function; Cellular and Extracellular Structural Biology; Molecular Interactions; Genomic and Metabolic Organization. The Delaware BRIN will support research in these areas within the framework of four cores: Administration, Bioinformatics, Centralized Research Instrumentation, and Training and Mentoring. The partner institutions are the University of Delaware (UD), the Delaware Biotechnology Institute (DBI), Delaware State University (DSU), a historically black university, Delaware Technical and Community College (DelTech), and Wesley College. With this supplement application, a new institutional partner joins the Delaware BRIN, the CCHS. The specific aims of the Delaware BRIN are to: a) Develop five centralized research instrumentation facilities, with training and access available to all members of the Delaware BRIN community, b) Provide mentoring and training for junior faculty and young investigators to increase NIH award rates; travel awards to attend regional and national scientific meetings, c) Advance undergraduate and graduate training programs in biotechnology / life sciences at UD, DSU, DelTech, CCHS and Wesley College through: new degree programs and summer research internships for graduate/undergraduate students; d) Implement and expand a sophisticated bioinformatics network that will: link partner institutions and BRIN cores; develop databases and servers; develop software tools; and conduct bioinformatics workshops.