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DETERMINATION OF STRUCTURE OF HIGH AFFINITY IGE RECEPTOR FROM MAST CELLS

DETERMINATION OF STRUCTURE OF HIGH AFFINITY IGE RECEPTOR FROM MAST CELLS
肥大细胞高亲和力 IGE 受体结构的测定
批准号:
6586528
负责人:
Theodore S Jardetzky
金额:
$14.32万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2002
资助国家:
美国
项目状态:
已结题
起止时间:
2002-03-01 至 2003-02-28

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中文摘要
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英文摘要
We have produced crystals of the extracellular domain of the high affinity IgE receptor from mast cells. This receptor provides a crucial link between soluble antibody and cell-based mechanisms of immunity. The receptor-IgE interaction is the key molecular recognition step associated with immediate-type hypersensitivities such as allergic and anaphylactic shock reactions. The crystals diffract weakly on laboratory sources and we are requesting time to collect high resolution data at SSRL.
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Discovery and engineering of novel anti-IgE disruptive inhibitors
  • 批准号:
    10353982
  • 项目类别:
  • 资助金额:
    $23.61万
  • 财政年份:
    2021
  • 负责人:
    Theodore S Jardetzky
  • 依托单位:
Discovery and engineering of novel anti-IgE disruptive inhibitors
  • 批准号:
    10495213
  • 项目类别:
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    $19.68万
  • 财政年份:
    2021
  • 负责人:
    Theodore S Jardetzky
  • 依托单位:
Human Cytomegalovirus Entry into Cells Mediated by Pentamer and Trimer Complexes
  • 批准号:
    10468251
  • 项目类别:
  • 资助金额:
    $75.42万
  • 财政年份:
    2020
  • 负责人:
    Theodore S Jardetzky
  • 依托单位:
Human Cytomegalovirus Entry into Cells Mediated by Pentamer and Trimer Complexes
  • 批准号:
    10687819
  • 项目类别:
  • 资助金额:
    $73.27万
  • 财政年份:
    2020
  • 负责人:
    Theodore S Jardetzky
  • 依托单位:
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