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STRUCTURAL STUDIES OF KLENTAQ DNA POLYMERASE & ITS COMPLEXES W/ DNA

STRUCTURAL STUDIES OF KLENTAQ DNA POLYMERASE & ITS COMPLEXES W/ DNA
KLENTAQ DNA 聚合酶的结构研究
批准号:
6586530
负责人:
SERGEY KOROLEV
金额:
$14.32万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2002
资助国家:
美国
项目状态:
已结题
起止时间:
2002-03-01 至 2003-02-28

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中文摘要
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英文摘要
The DNA polymerase from Thermophyllus aquaticus (Taq) is a thermostable enzyme extensively used to generate DNA fragments by the polymerase chain reaction (PCR). Our goal is to study the structural basis for thermostability of this polymerase. An explanation for thermostability may only be obtained by determining the 3-D structure of the enzyme. The aim of the current investigation is to study crystallographically the KlenTaq DNA polymerase and its complexes with DNA.
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Structural studies of PARK14
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    9180460
  • 项目类别:
  • 资助金额:
    $22.73万
  • 财政年份:
    2016
  • 负责人:
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Structure-functional studies of recombination/replication mediator proteins
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    7931189
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    2009
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    SERGEY KOROLEV
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Structure-functional studies of recombination/replication mediator proteins
  • 批准号:
    7617034
  • 项目类别:
  • 资助金额:
    $23.41万
  • 财政年份:
    2006
  • 负责人:
    SERGEY KOROLEV
  • 依托单位:
Structure-functional studies of recombination/replication mediator proteins
  • 批准号:
    7227753
  • 项目类别:
  • 资助金额:
    $23.41万
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