ADOLESCENT TRIAL NETWORK FOR HIV/AIDS BALTIMORE

巴尔的摩艾滋病毒/艾滋病青少年试验网络

• 批准号: 6637419
• 负责人: Ligia Peralta
• 金额: $ 49.77万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-16 至 2006-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6637419
• 关键词: AIDS; AIDS /HIV diagnosis; AIDS /HIV test; AIDS education /prevention; HIV infections; adolescence (12-20); clinical trials; cooperative study; counseling; disease /disorder proneness /risk; health behavior; health care referral /consultation; human subject; longitudinal human study; medical outreach /case finding; patient oriented research; pediatric AIDS; sex behavior; social service; substance abuse related disorder; urban area; young adult human (21-34)

DESCRIPTION: (provided by applicant): The University of Maryland STAR TRACK Adolescent HIV Program (STAR TRACK Program) is a clinical and research unit with significant experience in the areas of adolescent HIV research. STAR TRACK is the only adolescent exclusive HIV service in the state of Maryland and has a comprehensive "one stop shopping" model of care, a state wide community outreach program, an HIV early identification program through an adolescent specific HIV counseling and testing unit, and a Youth Care Network that serves as referral network for both HIV+ and HIV-youths. Our program has been one of 15 sites of the Adolescent HIV/AIDS Research Network since 1994 with a successful track record of recruitment, retention, site performance, quality assurance. Our PI, study coordinators, and Youth Community Advisory Board member have productively participated in and contributed towards the AMHARN mission and its goals. Our program has extensive experience in the recruitment and retention of HIV+ and HIV-adolescents in clinical care and research, and an active caseload of 105 HIV+ youths (many of whom have research experience) and 125 HIV-youths. STAR TRACK has strong clinical and research collaborations with other clinical sites for a total of 180 HIV infected young people under the age of 24. Our program has highly experienced adolescent researchers and study coordinators as well as basic and clinical researchers of the Division of Pediatric Immunology and the Institute of Human Virology of the University of Maryland. These investigators have an extensive track record of leadership in multicenter collaborative trials. The tight interface between community outreach, early identification of HIV, linkage to care and research, and comprehensive primary and subspecialty care, intrinsic to STAR TRACK?s structure, facilitates the major goals of the ATN. These relationships also provide a great structure to expand subject recruitment. This application details the current clinical and research capacity of the Adolescent Medicine Trial Unit (AMTU) to conduct research protocols related to the primary, secondary and tertiary prevention of HIV. High-risk populations available for this research include high-risk sexual minority and heterosexual youths, as well as incarcerated and substance abusing youths. In addition, it includes youths in transitional housing situation and school dropouts. Furthermore, the strong collaboration with an experienced laboratory, database manager and other University of Maryland scientists with expertise in HIV clinical trials and vaccine development provides an optimal environment for enriching the basic science and laboratory-based agenda of the ATN.

描述：（由申请人提供）：马里兰州大学星星轨道 青少年艾滋病毒方案（星星TRACK方案）是一个临床和研究单位 在青少年艾滋病毒研究领域拥有丰富经验。星星 TRACK是马里兰州唯一的青少年专属艾滋病毒服务机构 并有一个全面的“一站式购物”模式的照顾，全州范围内 社区外展计划，通过一个艾滋病毒早期识别计划， 青少年艾滋病毒咨询和检测单位，以及青年关怀网络 作为艾滋病毒阳性和艾滋病毒阳性青年的转介网络。我们的计划 自1994年以来，它一直是青少年艾滋病毒/艾滋病研究网络的15个网站之一 拥有成功的招聘、保留、现场性能、 质量保证。我们的PI，学习协调员和青年社区咨询 董事会成员富有成效地参与并促进了 AMHARN使命及其目标。我们的项目在以下方面拥有丰富的经验： 在临床护理中招募和保留艾滋病毒阳性和艾滋病毒阴性青少年， 研究，以及105名艾滋病毒阳性青年（其中许多人 研究经验）和125名艾滋病毒感染青年。星星TRACK具有强大的临床和 与其他临床研究中心合作，共180例艾滋病毒感染者 24岁以下的感染者。我们的节目经验丰富 青少年研究人员和研究协调员以及基础和临床 儿科免疫学部和人类免疫学研究所的研究人员 马里兰州大学的病毒学。这些调查人员有广泛的 在多中心协作试验中的领导记录。紧张 社区外展、艾滋病毒的早期识别、 护理和研究，以及综合初级和专科护理，内在 到星星轨道？的结构，促进ATN的主要目标。这些 关系也为扩大受试者招募提供了一个很好的结构。 该申请详细介绍了目前的临床和研究能力， 青少年医学试验单位（AMTU）进行研究方案， 艾滋病毒的一级、二级和三级预防。高危人群 可用于这项研究的包括高风险的性少数和异性恋者 青少年，以及被监禁和滥用药物的青少年。此外还 包括处于过渡性住房状况的青年和辍学者。 此外，与经验丰富的实验室、数据库 经理和其他马里兰州大学的科学家在艾滋病毒方面的专业知识 临床试验和疫苗开发提供了最佳环境， 丰富ATN的基础科学和实验室议程。