Nanostructure surveys of natural and biomimetic dental tissues by 3D SAXS tensor tomography

为了更好地利用现有材料并创造新的和更好的产品，我们寻求了解自然材料的行为，我们需要能够在整个身体每一个不断提高的分辨率水平上确定结构。在这份提案中，我们寻求在Beamline I22开发和应用先进的3D SAXS张量层析成像技术，以创造一种独特的能力，显著扩展我们的表征专业知识，并开辟新的研究途径。该项目的目标是利用酸诱导模型，深入了解牙本质脱矿不同阶段纳米纤维状胶原结构的演变，并了解影响新型生物灵感层次化牙科复合材料机械性能的关键结构因素，旨在仿生设计可靠的牙科修复体和其他牙本质类材料。虽然这种仪器将实现的新科学跨越了一系列看似不同的领域(最初来自牙科材料)，但共同方法的开发将联合不同的用户，并为研究想法的交叉交流提供一种机制。此外，该项目将作为导致钻石II的新科学开发的基础，并预测新环的低发射率特性。

In our quest to understand the behaviour of natural materials in order to make better use of existing ones and create novel and superior products, we need to be able to determine the structure at every increasing levels of resolution throughout the body. In this proposal, we seek to develop and apply the advanced 3D SAXS tensor tomography at beamline I22 to create a unique capability that will significantly extend our characterisation expertise and open up new avenues of research. The objective of the project is to enable significant understanding of the nanofibrillar collagen structural evolution at different stages of dentine demineralisation using an acid induced model, and the understanding of key structural factors that affect the mechanical performance of novel bio-inspired hierarchical dental composite aiming for biomimetic design of reliable dental prosthesis and other dentine-like materials. Whilst the new science that this instrumentation will enable spans a range of seemingly disparate areas (initially from dental materials), the development of common methodologies will unite the various users and provide a mechanism for the cross-fertilisation of research ideas. Additionally, this project will serve as a basis for new science exploitation leading towards Diamond II and the projected low emittance properties of the new ring.