MBRS SCORE Program at the Ponce School of Medicine

庞塞医学院的 MBRS SCORE 项目

• 批准号: 7919934
• 负责人: Jaime L Matta
• 金额: $ 34.47万
• 依托单位: PONCE SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-10 至 2010-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7919934
• 关键词: MBRS; SCORE; Program; Ponce; Medicine

In the present application we are requesting funds to continue the support of the MBRS SCORE'. Program at the Ponce School of Medicine. The MBRS SCORE Program, since its implementation in 19854, has been the driving force in developing and strengthening the graduate program in Biomedical Sciences and in creating a vigorous research environment that has resulted in providing the resources to support studies in immunology, cellular and molecular biology, epidemiology, parasitology, toxicology neurosciences, HIV/AIDS, and human physiology. The goal of this MBRS-SCORE Program proposal is to increase the biomedical research productivity, the scientific competitiveness and recognition of the faculty, by providing first rate research and development opportunities and in creating a stimulating research atmosphere in this Institution. The proposal contains a total of twenty regular subprojects and three pilot projects involving more than thirty-seven investigators, seven of which have been recently recruited into the School. The subprojects that make up this Program includes basic, psychological, and clinical research initiatives from faculty in the departments of Biochemistry, Microbiology, Pharmacology and Toxicology, Physiology, Clinical Psychology, and Public Health. The diverse projects include such areas as human genetics, protein folding, neurosciences, cancer biology, asthma, aging, signal transduction, cancer, gastrointestinal physiology, toxicology, HIV/AIDS, neuroscience, endometriosis, epidemiology, and psychology. These research projects will be sustained by an administrative component and by technical support personnel that includes collaborators, consultants, research associates, laboratory supervisors and research assistants. In addition, some of the activities will be complementary to other minority targeted programs in the Institutions such as the NIH-RCMI Program. Progress in the Specific Aims of each subproject and in the overall aims of the Program will be evaluated yearly in a formative report, and at the end in a summative document. Progress and achievements of the proposed program will be assessed continuously through an ongoing formative evaluation intended to provide information to improve the performance in the various program subprojects and through a summative evaluation that will finally assess the Program's success and the extent to which the completed project has met its goals. Both the evaluation of the implementation to assess whether the Program is being conducted as planned and the process, the

在本申请中，我们要求资金继续支持MBRS评分。在Ponce 医学院的。MBRS SCORE计划自1985年实施以来，一直是 发展和加强生物医学科学的研究生课程，并创造一个充满活力的研究 环境，导致提供资源，以支持免疫学，细胞和分子 生物学、流行病学、寄生虫学、毒理学、神经科学、艾滋病毒/艾滋病和人类生理学。这个目标 MBRS-SCORE计划的提出是为了提高生物医学研究的生产力、科学竞争力 和教师的认可，通过提供一流的研究和发展机会，并在创造一个 在这个研究所里营造研究氛围。该提案共包括20个经常性分项目， 三个试点项目，涉及37名以上调查员，其中7名最近被征聘到 该校构成该计划的子项目包括基础、心理和临床研究计划 来自生物化学、微生物学、药理学和毒理学、生理学、临床 心理学和公共卫生。不同的项目包括人类遗传学，蛋白质折叠， 神经科学，癌症生物学，哮喘，衰老，信号转导，癌症，胃肠生理学，毒理学， 艾滋病毒/艾滋病，神经科学，子宫内膜异位症，流行病学和心理学。 这些研究项目将由一个行政部门和技术支助人员维持， 包括合作者、顾问、研究助理、实验室主管和研究助理。此外，本发明还提供了一种方法， 其中一些活动将补充其他少数民族为目标的方案，如机构， NIH-RCMI项目。每个子项目的具体目标和方案总体目标的进展情况将 每年在形成性报告中进行评估，并在总结性文件中进行评估。进展和成就 拟议的计划将通过持续的形成性评估进行持续评估，旨在提供 信息，以提高各计划子项目的绩效，并通过总结性评估， 将最终评估该计划的成功和完成的项目达到其目标的程度。两者 评估实施情况，以评估该计划是否按计划进行以及流程、

项目成果

Immunoblot analysis and comparative IgE responses of atopic patients to extracts of the domestic mite Blomia tropicalis.

特应性患者对家螨热带螨提取物的免疫印迹分析和比较 IgE 反应。

• 发表时间: 2006
• 期刊: Puerto Rico health sciences journal
• 影响因子: 0.5
• 作者: Montealegre,Federico;Goth,Kerstin;Hart,Barbara
• 通讯作者: Hart,Barbara

The suppression of T cell function and NF(kappa)B expression by serine protease inhibitors is blocked by N-acetylcysteine.

N-乙酰半胱氨酸可阻断丝氨酸蛋白酶抑制剂对 T 细胞功能和 NF(kappa)B 表达的抑制。

• DOI: 10.1006/cimm.1996.0258
• 发表时间: 1996
• 期刊: Cellular immunology
• 影响因子: 4.3
• 作者: Breithaupt,TB;Vazquez,A;Baez,I;Eylar,EH
• 通讯作者: Eylar,EH

The association of DNA Repair with breast cancer risk in women. A comparative observational study.

DNA修复与女性乳腺癌风险的关联。比较观察性研究。

• DOI: 10.1186/1471-2407-12-490
• 发表时间: 2012-10-22
• 期刊: BMC cancer
• 影响因子: 3.8
• 作者: Matta J;Echenique M;Negron E;Morales L;Vargas W;Gaetan FS;Lizardi ER;Torres A;Rosado JO;Bolaños G;Cruz JG;Laboy J;Barnes R;Medina SS;Romero A;Martinez R;Dutil J;Suarez E;Alvarez-Garriga C;Bayona M
• 通讯作者: Bayona M

Microstimulation reveals opposing influences of prelimbic and infralimbic cortex on the expression of conditioned fear.

• DOI: 10.1101/lm.306106
• 发表时间: 2006-11
• 期刊: Learning & memory
• 影响因子: 2
• 作者: Ivan Vidal-Gonzalez;Benjamín Vidal-Gonzalez;S. Rauch;G. Quirk

Apolipoprotein E Allelic Frequency Altered in Women with Early-onset Breast Cancer

• DOI: 10.1177/117822341000400005
• 发表时间: 2010-01
• 期刊: Breast Cancer : Basic and Clinical Research
• 作者: Tirtsa Porrata-Doria;J. Matta;Summer F Acevedo