MBRS SCORE Program at the Ponce School of Medicine

庞塞医学院的 MBRS SCORE 项目

• 批准号: 7919934
• 负责人: Jaime L Matta
• 金额: $ 34.47万
• 依托单位: PONCE SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-10 至 2010-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7919934
• 关键词: MBRS; SCORE; Program; Ponce; Medicine

In the present application we are requesting funds to continue the support of the MBRS SCORE'. Program at the Ponce School of Medicine. The MBRS SCORE Program, since its implementation in 19854, has been the driving force in developing and strengthening the graduate program in Biomedical Sciences and in creating a vigorous research environment that has resulted in providing the resources to support studies in immunology, cellular and molecular biology, epidemiology, parasitology, toxicology neurosciences, HIV/AIDS, and human physiology. The goal of this MBRS-SCORE Program proposal is to increase the biomedical research productivity, the scientific competitiveness and recognition of the faculty, by providing first rate research and development opportunities and in creating a stimulating research atmosphere in this Institution. The proposal contains a total of twenty regular subprojects and three pilot projects involving more than thirty-seven investigators, seven of which have been recently recruited into the School. The subprojects that make up this Program includes basic, psychological, and clinical research initiatives from faculty in the departments of Biochemistry, Microbiology, Pharmacology and Toxicology, Physiology, Clinical Psychology, and Public Health. The diverse projects include such areas as human genetics, protein folding, neurosciences, cancer biology, asthma, aging, signal transduction, cancer, gastrointestinal physiology, toxicology, HIV/AIDS, neuroscience, endometriosis, epidemiology, and psychology. These research projects will be sustained by an administrative component and by technical support personnel that includes collaborators, consultants, research associates, laboratory supervisors and research assistants. In addition, some of the activities will be complementary to other minority targeted programs in the Institutions such as the NIH-RCMI Program. Progress in the Specific Aims of each subproject and in the overall aims of the Program will be evaluated yearly in a formative report, and at the end in a summative document. Progress and achievements of the proposed program will be assessed continuously through an ongoing formative evaluation intended to provide information to improve the performance in the various program subprojects and through a summative evaluation that will finally assess the Program's success and the extent to which the completed project has met its goals. Both the evaluation of the implementation to assess whether the Program is being conducted as planned and the process, the

在目前的申请中，我们要求资金继续支持MBRS SCORE。庞塞学院的项目

项目成果

Immunoblot analysis and comparative IgE responses of atopic patients to extracts of the domestic mite Blomia tropicalis.

特应性患者对家螨热带螨提取物的免疫印迹分析和比较 IgE 反应。

• 发表时间: 2006
• 期刊: Puerto Rico health sciences journal
• 影响因子: 0.5
• 作者: Montealegre,Federico;Goth,Kerstin;Hart,Barbara
• 通讯作者: Hart,Barbara

The suppression of T cell function and NF(kappa)B expression by serine protease inhibitors is blocked by N-acetylcysteine.

N-乙酰半胱氨酸可阻断丝氨酸蛋白酶抑制剂对 T 细胞功能和 NF(kappa)B 表达的抑制。

• DOI: 10.1006/cimm.1996.0258
• 发表时间: 1996
• 期刊: Cellular immunology
• 影响因子: 4.3
• 作者: Breithaupt,TB;Vazquez,A;Baez,I;Eylar,EH
• 通讯作者: Eylar,EH

The association of DNA Repair with breast cancer risk in women. A comparative observational study.

DNA修复与女性乳腺癌风险的关联。比较观察性研究。

• DOI: 10.1186/1471-2407-12-490
• 发表时间: 2012-10-22
• 期刊: BMC cancer
• 影响因子: 3.8
• 作者: Matta J;Echenique M;Negron E;Morales L;Vargas W;Gaetan FS;Lizardi ER;Torres A;Rosado JO;Bolaños G;Cruz JG;Laboy J;Barnes R;Medina SS;Romero A;Martinez R;Dutil J;Suarez E;Alvarez-Garriga C;Bayona M
• 通讯作者: Bayona M

Microstimulation reveals opposing influences of prelimbic and infralimbic cortex on the expression of conditioned fear.

• DOI: 10.1101/lm.306106
• 发表时间: 2006-11
• 期刊: Learning & memory
• 影响因子: 2
• 作者: Ivan Vidal-Gonzalez;Benjamín Vidal-Gonzalez;S. Rauch;G. Quirk

Apolipoprotein E Allelic Frequency Altered in Women with Early-onset Breast Cancer

• DOI: 10.1177/117822341000400005
• 发表时间: 2010-01
• 期刊: Breast Cancer : Basic and Clinical Research
• 作者: Tirtsa Porrata-Doria;J. Matta;Summer F Acevedo