Integration of Mixtures Toxicology and Statistics

描述(由申请人提供) 这笔培训补助金的目的是培训生物统计学家 在跨学科协作团队中工作，解决问题 与解释化学混合物的影响有关。一把钥匙 这项事业的成功是Key公司努力的结果 该领域的科学家(混合毒理学家和生物统计学家) 与生物统计学系学员的化学混合物。这个 培训目标是让学员了解和体验工作 关于化学品混合物的统计问题。这些实习生将成为 有资格在政府机构、学术界、 以及正确评估药物/化学相互作用的行业 变得越来越重要。 学员将是生物统计学系的博士生 在弗吉尼亚联邦的弗吉尼亚医学院校区 大学(VCU)，他们将在那里接受博士培训 生物统计学学科。将获得更多的专业知识 通过与领域相关的论文主题的工作 混合物和通过外部船舶与毒物学家和/或风险 在化学混合物领域积极开展工作的评估员。穿过 这些外部项目，学生将获得合作经验 与一组专家一起从事涉及化学混合物的研究。 受训人员将协助设计混合物研究、进行 进行适当的电力分析、分析结果数据并编写报告 讲师对结果有适当的解释。此外, 受训者将与正在开发的生物统计学家合作 设计和分析中涉及的问题的统计方法 从对化学品混合物的研究中产生的数据，以及谁是 对混合研究的数据进行分析。

DESCRIPTION (provided by applicant) The objective of this training grant is to train biostatisticians to work in inter-disciplinary collaborative teams addressing the problems associated with explaining the effects of chemical mixtures. A key to the success of this venture is the joining of the efforts of key scientists (mixtures toxicologists and biostatisticians) in the field of chemical mixtures with trainees from a department of biostatistics. The goal is for trainees to gain an understanding of and experience working on statistical issues of mixtures of chemicals. These trainees will be qualified to hold unique positions in governmental agencies, academia, and industry where properly evaluating drug/chemical interactions is becoming increasingly important. The trainees will be Ph.D. students in the Department of Biostatistics at the Medical College of Virginia campus of Virginia Commonwealth University (VCU), where they will pursue doctoral training in the discipline of biostatistics. Additional expertise will be achieved through work on dissertation topics that are pertinent to the field of mixtures and through externships with toxicologists and/or risk assessors actively working in the area of chemical mixtures. Through these externship programs, students will gain experience collaborating with a team of experts working on studies involving chemical mixtures. The trainees will assist in the design of mixture studies, conduct appropriate power analyses, analyze resulting data and write reports for the preceptor with proper interpretation of the results. In addition, the trainees will collaborate with biostatisticians who are developing statistical methodology for issues involved in the design and analysis of data resulting from studies of mixtures of chemicals and who are conducting analyses of data from mixture studies.