Training Program in Pediatric Gastroenterology/nutrition

描述(由申请人提供)： 这是申请继续支持加州大学旧金山分校(UCSF)的儿科胃肠病和营养学培训计划。在过去的29年里，该项目一直得到持续资助，是NIH在美国西部唯一支持这一专业的培训机构。该计划的目标是为儿童胃肠病学、肝病学和营养学方面的生产性研究培养学员。大多数毕业生(70%)都进入了学术生涯。五年前，这笔培训补助金进行了重组，以利用加州大学旧金山分校和斯坦福大学的合并。随着合并的结束，该计划进行了重新调整，以承认目前的学术环境，即要求所有受训人员在新的医疗保健服务和基于价值的研究的背景下了解儿科疾病的分子和遗传学基础。该计划现在致力于培训高度精选的儿科胃肠病学术前景，使其在团队框架内发挥作用，协调医学科学家与分子和细胞生物学家、生理学家、生物工程师、人种学家和生物伦理学家的努力。目前的申请提出了一种更系统和更精简的方法，即(1)在两条主要职业道路--基础研究和临床研究--内进行培训，以及(2)在任何时候减少该计划的受训人数。学员在自己的研究项目背景下，接受2-3年基础实验室或临床研究方法方面的强化教学和实践指导。该课程将胃肠道结构和功能发育方面的教学与实验室和/或临床研究的实践经验结合起来，重点研究生长和分化的生物力学，以及干扰有序发育的障碍。教育练习包括正式讲座、学员准备的研讨会、跨学科演讲和正在进行的项目的非正式讨论。学员参加生物统计学、计算机科学、生物研究原理和调查伦理学等课程。每个学员都要完成一项必修研究项目(S)，由经验丰富的导师指导。要求有医学博士学位和3年的儿科临床实习经验。拥有博士学位和明确的与发展胃肠病学或营养学相关的职业目标的申请者也有资格。该计划在儿科胃肠病、肝病和营养科实施，但利用了整个加州大学旧金山分校的科学资源。受训人员可以在多学科环境中接触讲师和实验室，以及相关的培训资源。培训计划的领导现在集中在梅尔文·B·海曼博士的直接监督下，并得到了用于指导和临床研究的新的K24拨款的支持。主要教员包括加州大学旧金山分校的两名副主任、核心分部教员和担任教授职务的高级教员导师。要求每年支持3名实习生

DESCRIPTION (provided by applicant): This is an application for continued support of the training program in Pediatric Gastroenterology and Nutrition at the University of California, San Francisco (UCSF). The program has been funded continuously for the past 29 years, and represents the only NIH-supported training facility for this specialty in the Western US. The program objective is to prepare trainees for productive research in pediatric gastroenterology, hepatology and nutrition. The majority of graduates (70%) have proceeded to academic careers. Five years ago, this training grant was restructured to take advantage of the merger between UCSF and Stanford University. With dissolution of the merger, the program is reconfigured in recognition of the current academic environment that requires all trainees to understand molecular and genetic bases of pediatric disorders within the context of new modalities of health care services and value-based research. The program now strives to train highly selected prospects for academic pediatric gastroenterology to function within a team framework, coordinating the efforts of medical scientists with molecular and cell biologists, physiologists, bioengineers, ethnographers, and bioethicists. The current application proposes a more systematic and streamlined approach by (1) training within two primary career paths - Basic Research and Clinical Research - and (2) reducing the number of trainees in the program at any one time. Trainees receive 2-3 years of intensive didactic and practical instruction in basic laboratory or clinical research methods in the context of their own research project. The curriculum combines instruction in developmental aspects of gastrointestinal structure and function with practical experience in laboratory- and/or clinically-based research focused on biomechanisms of growth and differentiation, and disorders which interfere with orderly development. Educational exercises include formal lectures, seminars prepared by trainees, interdisciplinary presentations, and informal discussions of ongoing projects. Trainees attend courses in biostatistics, computer science, principles of bioresearch, and investigational ethics. Each trainee pursues an obligatory research project(s) supervised by experienced preceptors. Requirements are a MD degree and 3 years of residency in clinical pediatrics. Applicants with PhD degrees and defined career goals related to developmental gastroenterology or nutrition are also eligible. The program is administered in the Division of Pediatric Gastroenterology, Hepatology and Nutrition, but utilizes the scientific resources of the entire UCSF campus. Trainees have access to preceptors and laboratories, with associated training resources, in a multidisciplinary environment. Training program leadership is now centralized under the direct supervision of Dr. Melvin B. Heyman, supported by a new K24 grant for mentoring and clinical investigation. Key faculty include two Associate Directors, Core Divisional Faculty and Senior Faculty Mentors with professorial positions at UCSF. Support for 3 trainees per year is requested