Environmental Field Emission Analytical SEM

描述（由申请人提供）：本申请是环境场发射分析扫描电子显微镜（EFESEM）。扫描电镜技术的最新进展为生物材料研究开辟了新的机会。场发射电子源和环境室的发展允许高分辨率成像（低至1nm）的湿，油，脏，脱气，低原子序数和非导电样品在其自然状态下，无需样品修饰或制备。这些能力是生物材料及其性能分析的一个突破，将构成新一代生物材料开发的一个组成部分。EFESEM是最通用的微结构表征仪器之一。当与多功能x射线分析仪相结合时，可以同时进行微化学分析。这个多用户设施将极大地加强六名NIH研究人员的研究。目前可供LBNL、UCSF和UCB教师使用的扫描电镜设备有限，而且能力差得多。

DESCRIPTION (provided by applicant): This application is for an Environmental Field Emission Analytical Scanning Electron Microscope (EFESEM). Recent advances in SEM technology open new opportunities for biomaterials research. The developments of field emission electron sources and environmental chambers allow high resolution imaging (down to 1 nm) of wet, oily, dirty, outgassing, low-atomic number and non-conductive samples in their natural state without sample modification or preparation. These capabilities are a breakthrough in the analysis of biomaterials and their performance that will constitute an integral part in the development of a new generation of biomaterials. The EFESEM is one of the most versatile instruments for microstructural characterization. When coupled with a multifunction x-ray analyzer, concurrent micro-chemical analysis is possible. This multiuser facility will greatly enhance the research of six NIH investigators. The SEM facilities available to LBNL, UCSF and UCB faculty at present are limited and much less capable. Funding is requested for the acquisition of a state-of-the-art environmental field emission SEM, a Hitachi 4300 SE/N. The proposal has received broad based support from departmental (LBNL, UCSF and UCB) faculty; personnel from laboratory groups representing six PI's with current funding from NIH are projected as users. The Proposed microscope will be housed at the National Center for Electron Microscopy (NCEM) at the Lawrence Berkeley National Laboratory (LBNL). NCEM is a world leader in the application of transmission electron microscopy to microstructural characterization which will guarantee maintenance and operation of the instrument at the top condition, and also excellent training and support for the users named on the grant proposal.