Environmental Field Emission Analytical SEM

描述（由申请人提供）：本申请用于环境场发射分析扫描电子显微镜（EFESEM）。扫描电镜技术的最新进展为生物材料研究提供了新的机会。场发射电子源和环境室的发展允许在其自然状态下对湿的、油性的、脏的、除气的、低原子序数的和非导电的样品进行高分辨率成像（低至1 nm），而无需样品修改或制备。这些能力是生物材料及其性能分析的突破，将构成新一代生物材料开发的一个组成部分。EFESEM是显微结构表征的最通用的仪器之一。当与多功能X射线分析仪结合使用时，可以同时进行微量化学分析。这种多用户设施将大大加强六名NIH研究人员的研究。目前，LBNL，UCSF和UCB教师可用的SEM设施有限，能力更差。 申请资金用于购置最先进的环境场发射扫描电镜，即Hitachi 4300 SE/N。该提案得到了部门（LBNL，UCSF和UCB）教师的广泛支持;来自实验室团体的人员代表六个PI，目前由NIH资助，预计将作为用户。申报的显微镜将存放在劳伦斯伯克利国家实验室（LBNL）的国家电子显微镜中心（NCEM）。NCEM是应用透射电子显微镜进行微观结构表征的世界领导者，这将保证仪器在最佳状态下的维护和操作，并为赠款提案中指定的用户提供出色的培训和支持。

DESCRIPTION (provided by applicant): This application is for an Environmental Field Emission Analytical Scanning Electron Microscope (EFESEM). Recent advances in SEM technology open new opportunities for biomaterials research. The developments of field emission electron sources and environmental chambers allow high resolution imaging (down to 1 nm) of wet, oily, dirty, outgassing, low-atomic number and non-conductive samples in their natural state without sample modification or preparation. These capabilities are a breakthrough in the analysis of biomaterials and their performance that will constitute an integral part in the development of a new generation of biomaterials. The EFESEM is one of the most versatile instruments for microstructural characterization. When coupled with a multifunction x-ray analyzer, concurrent micro-chemical analysis is possible. This multiuser facility will greatly enhance the research of six NIH investigators. The SEM facilities available to LBNL, UCSF and UCB faculty at present are limited and much less capable. Funding is requested for the acquisition of a state-of-the-art environmental field emission SEM, a Hitachi 4300 SE/N. The proposal has received broad based support from departmental (LBNL, UCSF and UCB) faculty; personnel from laboratory groups representing six PI's with current funding from NIH are projected as users. The Proposed microscope will be housed at the National Center for Electron Microscopy (NCEM) at the Lawrence Berkeley National Laboratory (LBNL). NCEM is a world leader in the application of transmission electron microscopy to microstructural characterization which will guarantee maintenance and operation of the instrument at the top condition, and also excellent training and support for the users named on the grant proposal.