Environmental Field Emission Analytical SEM

描述(申请人提供)：本申请为环境场致发射分析扫描电子显微镜(EFESEM)。扫描电子显微镜技术的最新进展为生物材料研究带来了新的机遇。场发射电子源和环境室的发展使湿的、油污的、肮脏的、放气的、低原子序数和非导电样品在其自然状态下能够高分辨率成像(低至1 nm)，而无需样品修改或制备。这些能力是在生物材料及其性能分析方面的突破，将构成新一代生物材料开发的组成部分。EFESEM是最通用的微结构表征仪器之一。当与多功能X射线分析仪配合使用时，可以同时进行微量化学分析。这一多用户设施将极大地加强六名NIH调查人员的研究。目前LBNL、加州大学旧金山分校和UCB教职员工可用的扫描电子显微镜设施有限，而且能力要差得多。 申请资金用于购买最先进的环境场致发射扫描电子显微镜，日立4300 SE/N。该提议得到了部门(LBNL、UCSF和UCB)教职员工的广泛支持；来自代表六个PI的实验室小组的人员预计将成为用户，目前由NIH提供资金。拟议中的显微镜将安置在劳伦斯伯克利国家实验室的国家电子显微镜中心(NCEM)。NCEM在将透射电子显微镜应用于微结构表征方面处于世界领先地位，这将确保仪器在最佳状态下的维护和操作，并为赠款提案中指定的用户提供出色的培训和支持。

DESCRIPTION (provided by applicant): This application is for an Environmental Field Emission Analytical Scanning Electron Microscope (EFESEM). Recent advances in SEM technology open new opportunities for biomaterials research. The developments of field emission electron sources and environmental chambers allow high resolution imaging (down to 1 nm) of wet, oily, dirty, outgassing, low-atomic number and non-conductive samples in their natural state without sample modification or preparation. These capabilities are a breakthrough in the analysis of biomaterials and their performance that will constitute an integral part in the development of a new generation of biomaterials. The EFESEM is one of the most versatile instruments for microstructural characterization. When coupled with a multifunction x-ray analyzer, concurrent micro-chemical analysis is possible. This multiuser facility will greatly enhance the research of six NIH investigators. The SEM facilities available to LBNL, UCSF and UCB faculty at present are limited and much less capable. Funding is requested for the acquisition of a state-of-the-art environmental field emission SEM, a Hitachi 4300 SE/N. The proposal has received broad based support from departmental (LBNL, UCSF and UCB) faculty; personnel from laboratory groups representing six PI's with current funding from NIH are projected as users. The Proposed microscope will be housed at the National Center for Electron Microscopy (NCEM) at the Lawrence Berkeley National Laboratory (LBNL). NCEM is a world leader in the application of transmission electron microscopy to microstructural characterization which will guarantee maintenance and operation of the instrument at the top condition, and also excellent training and support for the users named on the grant proposal.