CLINICAL RESEARCH CURRICULUM AWARD

此申请代表杜兰大学对研究课程奖（RFA OD-00-002）的机构回应。该奖项是由美国国立卫生研究院设立的，旨在通过培养有兴趣成为有效临床科学家的个人来解决日益严重的国家对学术临床研究人员短缺的担忧。本申请的总体目标是获得临床研究课程奖（CRCA），该奖项将支持建立一个新的、结构化的2年项目，从杜兰大学和泽维尔大学有前途的高级学员中培养有效的临床研究人员。杜兰大学CRCA项目代表了一个新开发的临床研究研究生培训项目，它是杜兰大学医学院、公共卫生学院和热带医学院的联合教育企业。该项目将汇集来自不同背景的学员，包括杜兰大学医学院的内科、儿科和外科、杜兰大学公共卫生和热带医学院、杜兰大学生物医学工程系和路易斯安那大学泽维尔大学药学院，以培养和培训具有创造性、独立性和生产力的临床研究人员。我们相信，向杜兰医学中心以外的其他学员开放CRCA课程（即包括具有生物医学工程药学博士学位和博士学位的学员）可以扩大学员群体，从而使更多的个人成为独立的、有资金支持的、忠诚的临床研究人员。作为该提案发展的一部分，杜兰大学医学中心设立了一个新的公共卫生（临床研究）2年制理学硕士课程。核心课程包括23个核心学分，包括生物统计学，流行病学，卫生系统管理，人类疾病机制，复杂疾病遗传学和治疗反应性课程，以及一系列研讨会（临床研究主题）和指导临床研究项目。虽然这是一个严格的课程，但MSPH（临床研究）课程的频率和顺序已被设计为确保CRCA学员能够参加并完成所有学位要求，完成指导的临床研究项目（向同行评审期刊提交手稿），并在正常培训期间满足各自临床培训计划的所有要求。CRCA奖将支持杜兰大学建立正式的临床研究课程，并建立专门的教师基础设施，为临床研究提供深入的指导。杜兰大学CRCA项目的受训者将获得必要的技能来设计和开展针对新兴医学治疗和技术、新诊断技术和病理生物学研究新方法的临床研究。

This application represents the institutional response from Tulane University to the Research Curriculum Award (RFA OD-00-002). This award was created by the NIH to address the growing national concern over the shortage of academic clinical investigators by training individuals interested in becoming effective clinical scientists. The overall goal of this application is to obtain a Clinical Research Curriculum Award (CRCA) that will support the establishment of a new, structured 2-year program to develop effective clinical researchers from promising advanced trainees at Tulane and Xavier Universities at an early phase of their training. The Tulane CRCA Program represents a newly-developed graduate training program in clinical investigation that is a joint educational enterprise of the Tulane Schools of Medicine and Public Health and Tropical Medicine. This program will bring together trainees from a diverse background, including Internal Medicine, Pediatrics and Surgery from Tulane Medical School, the Tulane School of Public Health and Tropical Medicine, the Tulane Department of Biomedical Engineering and the Xavier University of Louisiana College of Pharmacy, to enable the development and training of creative, independent, and productive clinical investigators. We believe the opening of the CRCA curriculum to additional trainees outside of Tulane Medical Center (i.e., inclusion of both trainees with Pharm D and PhD degrees in biomedical engineering) expands the group of trainees resulting in a broad base of individuals to become independent, funded and committed clinical investigators. As part of the development of this proposal, a new Master of Science in Public Health (Clinical Research) 2- year program at Tulane University Medical Center has been established. The core curriculum includes 23 core credit hours and include courses in biostatistics, epidemiology, health systems management, mechanisms of human disease, genetics of complex disorders and therapeutic responsiveness plus a seminar series (Topics in Clinical Research) and a mentored clinical research project. Although this is a rigorous curriculum, the frequency and sequence of the MSPH (Clinical Research) curriculum has been designed to ensure that the CRCA trainees will be able to attend and complete all degree requirements, complete a mentored clinical research project (with submission of a manuscript to a peer-reviewed journal) and meet all requirements of their respective clinical training programs during their normal training period. The CRCA Award will support the establishment of a formal Clinical Research Curriculum at Tulane University and create an infrastructure of dedicated faculty who provide in-depth mentorship of clinical research. Trainees in the Tulane CRCA Program will acquire the necessary skills to design and conduct clinical investigations into emerging medical treatments and technologies, new diagnostic techniques, and new approaches to the study of pathobiology.