CLINICAL RESEARCH CURRICULUM AWARD

这份申请代表了杜兰大学对研究课程奖(RFA OD-00-002)的机构回应。该奖项由美国国立卫生研究院设立，旨在通过培训有兴趣成为有效的临床科学家的个人来解决国家对学术临床研究人员短缺的日益增长的担忧。这项申请的总体目标是获得临床研究课程奖(CRCA)，这将支持建立一个新的、结构化的2年期计划，从杜兰大学和泽维尔大学有前途的高级实习生培养有效的临床研究人员，在他们的培训早期阶段。杜兰CRCA项目是杜兰大学医学院、公共卫生和热带医学院的联合教育项目，是一项新开发的临床研究研究生培训项目。该计划将汇集来自杜兰医学院、杜兰公共卫生和热带医学院、杜兰生物医学工程系和路易斯安那泽维尔大学药学院的不同背景的学员，包括内科、儿科和外科，以开发和培训富有创造力、独立和多产的临床研究人员。我们相信，向杜兰医学中心以外的其他受训人员开放CRCA课程(即包括拥有生物医学工程博士学位和制药博士学位的受训人员)将扩大受训人员群体，从而使更多的个人成为独立、有资金和忠诚的临床研究人员。作为这项提议发展的一部分，杜兰大学医学中心设立了一个新的公共卫生科学硕士(临床研究)2年制课程。核心课程包括23个核心学分，包括生物统计学、流行病学、卫生系统管理、人类疾病机制、复杂疾病遗传学和治疗反应性课程，以及一系列研讨会(临床研究主题)和一个有指导的临床研究项目。尽管这是一个严格的课程，但MSPH(临床研究)课程的频率和顺序已被设计为确保CRCA学员能够参加并完成所有学位要求，完成指导临床研究项目(向同行评议的期刊提交手稿)，并在正常培训期间满足各自临床培训计划的所有要求。CRCA奖将支持在杜兰大学建立正式的临床研究课程，并建立一个专门的教职员工基础设施，提供深入的临床研究指导。杜兰CRCA计划的学员将获得必要的技能，以设计和进行对新兴医疗方法和技术、新诊断技术和病理生物学研究的新方法的临床调查。

This application represents the institutional response from Tulane University to the Research Curriculum Award (RFA OD-00-002). This award was created by the NIH to address the growing national concern over the shortage of academic clinical investigators by training individuals interested in becoming effective clinical scientists. The overall goal of this application is to obtain a Clinical Research Curriculum Award (CRCA) that will support the establishment of a new, structured 2-year program to develop effective clinical researchers from promising advanced trainees at Tulane and Xavier Universities at an early phase of their training. The Tulane CRCA Program represents a newly-developed graduate training program in clinical investigation that is a joint educational enterprise of the Tulane Schools of Medicine and Public Health and Tropical Medicine. This program will bring together trainees from a diverse background, including Internal Medicine, Pediatrics and Surgery from Tulane Medical School, the Tulane School of Public Health and Tropical Medicine, the Tulane Department of Biomedical Engineering and the Xavier University of Louisiana College of Pharmacy, to enable the development and training of creative, independent, and productive clinical investigators. We believe the opening of the CRCA curriculum to additional trainees outside of Tulane Medical Center (i.e., inclusion of both trainees with Pharm D and PhD degrees in biomedical engineering) expands the group of trainees resulting in a broad base of individuals to become independent, funded and committed clinical investigators. As part of the development of this proposal, a new Master of Science in Public Health (Clinical Research) 2- year program at Tulane University Medical Center has been established. The core curriculum includes 23 core credit hours and include courses in biostatistics, epidemiology, health systems management, mechanisms of human disease, genetics of complex disorders and therapeutic responsiveness plus a seminar series (Topics in Clinical Research) and a mentored clinical research project. Although this is a rigorous curriculum, the frequency and sequence of the MSPH (Clinical Research) curriculum has been designed to ensure that the CRCA trainees will be able to attend and complete all degree requirements, complete a mentored clinical research project (with submission of a manuscript to a peer-reviewed journal) and meet all requirements of their respective clinical training programs during their normal training period. The CRCA Award will support the establishment of a formal Clinical Research Curriculum at Tulane University and create an infrastructure of dedicated faculty who provide in-depth mentorship of clinical research. Trainees in the Tulane CRCA Program will acquire the necessary skills to design and conduct clinical investigations into emerging medical treatments and technologies, new diagnostic techniques, and new approaches to the study of pathobiology.