THE ROLE OF CO-MORBID MENTAL DISORDERS IN LYME DISEASE

共病精神障碍在莱姆病中的作用

• 批准号: 6724865
• 负责人: Afton L Hassett
• 金额: $ 12.9万
• 依托单位: UNIV OF MED/DENT NJ-R W JOHNSON MED SCH
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-05-01 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6724865
• 关键词: Lyme disease; behavioral /social science research tag; comorbidity; disease /disorder proneness /risk; human subject; longitudinal human study; mental disorders; pathologic process; patient oriented research; postdoctoral investigator; psychosomatic disorders; questionnaires

DESCRIPTION (provided by investigator): Committed to a career in behavioral science research, the candidate's immediate goals are to obtain high quality didactic training and additional mentored experience related to interdisciplinary research. Long term career goals include exploring the role of co-morbid mental disorders and related psychological processes in rheumatologic illness and eventually becoming an expert on medically unexplained symptom syndromes across specialties. Current research is based on the candidate's stress-diathesis theoretical model for the "psychopathogenesis" of unexplained symptom syndromes present in rheumatology, i.e., Post Lyme Disease and fibromyalgia. The K08 Award would allow the candidate to devote 80 percent of her time to research and training. UMDNJ-Robert Wood Johnson Medical School is an outstanding environment in which to conduct this type of research. In addition to traditional biomedical research, many faculty members are actively exploring the role of psychological processes in health and illness. Mentorship would be provided by two such exceptional faculty, Javier I. Escobar, MD, Chairman of Psychiatry and Leonard H. Sigal MD, Chief of Rheumatology and Director of the Lyme Disease Center at UMDNJ-RWJMS. In addition to superior mentored clinical research experience, the candidate will receive advanced training in research methodology, statistical analysis, the responsible conduct of research, and neuroscience. Training highlights include statistical analyses through the Department of Statistics at Rutgers University and Neuroscience coursework at Princeton University. Mentored experience in research will consist of two studies. Study 1 will assess the co-morbid clinical disorders (Axis I) and pathological personality traits (Axis II) of patients who attribute chronic symptoms to Lyme disease. Study 2 prospectively examines newly diagnosed Lyme disease patients for co-morbid mental disorders and related cognitive/behavioral processes at baseline and follows them for one year. Our goal is to identify risk factors for the development of chronic symptoms ascribed to Lyme disease after adequate antibiotic treatment.

描述（由研究者提供）：致力于行为学研究