HSPH NIEHS Center for Environmental Health

描述(由申请人提供)： 这一修改后的申请旨在尽可能全面地回应网站访问者和后续审查小组的关切。因此，8个学科研究核心已被3个多学科综合研究核心所取代。设施核心得到加强。中心成员资格的要求和好处已经明确。领导力问题已经得到解决。总而言之，由于这些结构性变化，这一计划已经重新聚焦并充满活力。 我们的中心促进了三个研究核心之间的积极合作：1)金属，2)城市和职业颗粒物，3)有机污染物。三个设施核心大大加强了研究核心的工作：1)生物分析，2)暴露和环境分析，3)环境统计。最后，通过社区外联和教育计划(COEP)，调查人员向公众提供他们的研究和知识的能力得到了极大的提高。中心的其他活动，如试点项目、新的研究人员和项目充实，都是实现整合、互动、多产和创新科学的催化机制。NIEHS中心的目标是产生与环境疾病的生理学、药理学、病理学、细胞生物学、分子生物学、遗传学和流行病学有关的新知识，并将这些知识应用于新的预防、诊断和治疗模式。研究人员通过各种方法实现这些目标，这些方法从分子和细胞研究到整个动物和人类群体的研究。通过NIEHS中心拨款提供的组织结构和资金支持，研究人员将增加他们在环境健康方面的研究和教学的影响。 总而言之，哈佛NIEHS环境健康中心仍然是波士顿环境研究和培训的主要焦点。NIEHS中心机制加强了联系，使哈佛NIEHS中心成为国家和国际网络的一部分。

DESCRIPTION (provided by applicant) : This amended application is designed to respond as completely as possible to concerns of the site visitors and of subsequent review groups. Accordingly, eight disciplinary Research Cores have been replaced by three multidisciplinary, integrated Research Cores. Facility Cores have been strengthened. The requirements and benefits of Center membership have been clarified. Leadership issues have been addressed. In toto, this program has been refocused and energized by these structural changes. Our Center fosters active collaborations among three Research Cores: 1) Metals, 2) Urban and Occupational Particles, and 3) Organic Pollutants. The work of the Research Cores is greatly enhanced by three Facility Cores: 1) Biological Analyses, 2) Exposures and Environmental Analyses, and 3) Environmental Statistics. Finally, the investigators' ability to make their research and knowledge available to the public is greatly enhanced by the Community Outreach and Education Program (COEP). Other Center activities, such as pilot projects, new investigators, and program enrichment are catalytic mechanisms to achieve integration, interaction, productive, and innovative science. The objectives of this NIEHS Center are to generate new knowledge relating to the physiology, pharmacology, pathology, cell biology, molecular biology, genetics, and epidemiology of environmental disease, and to apply this knowledge to new modalities of prevention, diagnosis, and therapy. The investigators achieve these objectives through a variety of approaches, which range from studies of molecules and cells to those of whole animals and human populations. Through the organizational structure and financial support provided by the NIEHS Center Grant, the investigators' will increase the impact of their research and teaching in environmental health. In toto, the Harvard NIEHS Center for Environmental Health continues to be a major focal point for environmental research and training in Boston. The NIEHS Center mechanism enhances connections and makes the Harvard NIEHS Center part of a national and international network.