课题基金 / 基金详情

Mechanisms of gene expression changes in lung cancer

Mechanisms of gene expression changes in lung cancer
肺癌基因表达变化的机制
批准号：
6954043
负责人：
Jin Jen
金额：
$0.0万
依托单位：
DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/6954043
关键词：
animal breeding biological signal transduction cooperative study disease /disorder model gene expression gene induction /repression genetic models genetic susceptibility genetically modified animals laboratory mouse life cycle lung neoplasms model design /development neoplasm /cancer genetics neoplastic transformation protein structure function transfection transforming growth factors

项目摘要

项目成果

Jin Jen的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
We are continuing our efforts to develop in vivo and in vitro models to better understand the mechanistic role of genes highly differentially expressed in lung cancers. We have generated transgenic mice carrying a gene, PGP9.5, which is often over expressed in lung cancers. We will closely examine these transgenic animals for potential tumor formation, life span changes, and to breed them with other lung cancer animal models. We are also using in vivo tissue culture systems to manipulate the expression of target genes using transfected plasmid constructs and siRNA technology.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Transcriptome map in non-small cell lung cancer
Gene expression profiles in lung cancer using cDNA array
Mechanisms of gene expression changes in lung cancer
Development of non-small cell lung cancer tissue microar
海外基金