"Smart Food" - The fulcrum in the energy balance equation

“智能食品”——能量平衡方程的支点

• 批准号: DP140101702
• 负责人: Prof Brian Oldfield
• 金额: $ 30.77万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP140101702
• 关键词: Smart; Food; fulcrum; energy; balance

The overall aim of the project is to establish how nutrients best promote an increase in energy expenditure and therefore weight loss. The experiments will be performed in rats using sophisticated technologies to introduce specific combinations of fats, carbohydrates or proteins directly into the stomach and then measure energy expenditure in a specialised type of energy burning rather than energy storing fat called brown adipose tissue. These experiments will uncover the mechanisms that relate nutrients in the stomach and activation of brown adipose tissue. They will provide a framework on which this project can build a knowledge of smart diets that will allow the effective control of body weight through modulation of energy expenditure.

该项目的总体目标是确定营养素如何最好地促进能量消耗的增加，从而减轻体重。实验将在老鼠身上进行，使用复杂的技术将脂肪、碳水化合物或蛋白质的特定组合直接引入胃中，然后测量一种特殊类型的能量燃烧而不是能量储存脂肪的能量消耗，这种脂肪被称为棕色脂肪组织。这些实验将揭示胃中的营养物质和棕色脂肪组织激活之间的关系机制。他们将提供一个框架，在此基础上，该项目可以建立智能饮食知识，通过调节能量消耗来有效控制体重。