Determinants of brown adipose tissue activation - implication for the regulation of energy balance and obesity

棕色脂肪组织活化的决定因素——对能量平衡和肥胖调节的影响

• 批准号: nhmrc : 1051109
• 负责人: Prof Brian Oldfield
• 金额: $ 41.15万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/determinants-brown-adipose-balance-obesity/112198
• 关键词: Determinants; brown; adipose; tissue; activation

One of the most important recent findings in the biology of obesity has been the revelation that brown adipose tissue (BAT) is present and functional in adult humans. Even more important, the amount of BAT seems to be related to the extent of obesity. The challenge now is to harness the means by which BAT is activated. Understanding the central neural control pathways and the rate limiting steps in the BAT itself will pave the way for new anti-obesity strategies.

最近在肥胖生物学中最重要的发现之一是揭示了棕色脂肪组织（BAT）在成年人中存在并起作用。更重要的是，BAT的数量似乎与肥胖的程度有关。目前的挑战是如何利用启动最佳可得技术的手段。了解BAT本身的中枢神经控制通路和限速步骤将为新的抗肥胖策略铺平道路。