Cancer Prevention: Translation of Molecular Revolution

描述（由申请人提供）：会议补助金支持要求为一个科学研讨会，题为“癌症预防：翻译的分子革命的诊所”。 讲习班将于2004年5月4日至6日在以色列海法的丹卡梅尔旅馆举行。 该讲习班的组织委员会由Dean Brenner博士（美国）、Gad Rennert博士（以色列）、Lawrence Freedman博士（以色列）和Jaak Janssens博士（比利时）组成。 这次会议的目标是： 1.将新的生物标志物发现方法与分子和群体流行病学以及癌症风险评估的见解联系起来。 2.审查新靶向化学预防剂和组合的最新数据，以开发新的临床试验范例，使用基于遗传和人群癌症风险评估确定的组中的生物标志物靶标。 3.促进美国、中东和欧洲科学家之间的合作，开发新的方法来干预乳腺癌和结直肠癌高危人群。 邀请与会者的依据是他们在科学学科、互动和协作经验和跟踪记录方面的多样性，以及改变先入为主的观念以适应新信息和重新制定未来研究计划的意愿。 会议是紧张的，仿照戈登会议。 它要求与会者作为一个小组保持隔离三天，密切合作。 安排膳食和空闲时间是为了增加与会者进行非正式互动的机会。 会议的特点是有限的20分钟讲座或45分钟的全体讲座，频繁的讨论时间，多个45至90分钟的小组讨论，长午餐和晚餐时间与重点小组会议，并结束会议“白色文件”，以创造关闭和重点的需要。 白色论文和演讲者论文将在适当的同行评审后提交给《癌症流行病学、生物标志物和预防》杂志发表。 通过深入的互动，与会者将相互熟悉，了解会议上所代表的不同学科的优势和劣势，并将认识和建立跨学科的互动，以创造必要的科学临界群众来推进该领域。

DESCRIPTION (provided by applicant): Meeting grant support is requested for a scientific workshop entitled "Cancer Prevention: Translation of the Molecular Revolution to the Clinic". This workshop will be held in the Dan Carmel Hotel in Haifa, Israel, on May 4-6, 2004. The organizing committee for this workshop consists of Drs. Dean Brenner (USA), Gad Rennert (Israel), Lawrence Freedman (Israel) and Jaak Janssens (Belgium). The objectives of this conference are: 1. To link new biomarker discovery methodologies with molecular and population epidemiologic and insights upon cancer risk assessment. 2. To review recent data from new targeted chemopreventive agents and combinations to develop new paradigms of clinical testing using biomarker targets in groups identified on the basis of genetic and population based cancer risk assessment. 3. To promote collaborations among scientists form the United States, the Middle East and Europe to develop novel approaches to intervene in subjects at high risk for the development of breast and colorectal cancer. Conferees are invited based upon their diversity in scientific discipline, interactive and collaborative experience and track-record, and perceived willingness to alter preconceptions in order to accommodate new information and reformulate future research plans. The Conference is intense and modeled after the Gordon Conferences. It requires conferees to remain segregated as a group for three days, working closely together. Meals and free time are structured to enhance the opportunities of conferees to interact informally. The Conference features a limited number of 20 minute lectures or 45 minute plenary lectures, frequent discussion periods, multiple 45 to 90 minute panel discussions, long lunch and dinner periods with focused group meetings, and an end of conference "White Paper" to create the need for closure and focus. The White Papers and speaker papers will be submitted for publication in Cancer Epidemiology, Biomarkers and Prevention after appropriate peer review. By intensively interacting, conferees will become familiar with each other, will understand the strengths and weaknesses of the diverse disciplines represented at the meeting, and will recognize and establish cross disciplinary interactions to create necessary scientific critical masses to advance the field.