Minority Research Enhancement Through Intl. Exchange

描述（由申请人提供）：优秀的本科生，博士预科生，医学生和教师从代表性不足的人口有机会在埃塞俄比亚，加纳，尼日利亚和意大利的研究密集型实验室进行有意义的生物医学研究。MHIRT在这些地点的研究项目在疟疾和血吸虫病领域特别强大，这是热带国家最重要的寄生虫病之一。因此，研究的目的是对用于治疗疟疾和蠕虫寄生虫的传统药用植物进行调查，并评估其在体内和体外抗疟疾和血吸虫病的抗疟疾和抗寄生虫功效。这些地点还提供了对原始雨林的广泛接触，并有能力进行环境微生物学、民族植物学和药理学方面的相关研究。位于意大利的研究中心提供细胞生物学、分子生物学和遗传学方面的专业知识。通过本科生研究增强计划（UREP），具有较强学术背景和动机的本科生将在由一位坚定的教师导师领导的两到四名学生组成的学科研究团队中工作。根据博士前国际富集计划（PIE），在尖端领域工作的候选人-细胞，分子，发育生物学，免疫学，纳米技术-将追求独立或指导研究。本研究得出的数据可用作候选人论文的一部分。与此同时，美国教师导师和他们的学生预计将与国际科学家开发强大的合作项目。每位MHIRT学员将以海报/平台演示、研讨会形式或出版物形式展示其研究数据和研究结果。拟议的计划是一个公式，为学生和教师的成功，并应加强本科生到研究生的过渡，并准备在生物医学科学的领导作用更多的代表性不足的群体。

DESCRIPTION (provided by applicant): Outstanding undergraduates, pre-doctoral, medical students and faculty from underrepresented populations have the opportunity to conduct meaningful biomedical research in research-intensive laboratories in Ethiopia, Ghana, Nigeria, and Italy. MHIRT research programs at these sites are particularly strong in areas of malaria and schistosomiasis, which are among the most important parasitic diseases in tropical countries. Therefore, the aim of the research is to carry out surveys on traditional medicinal plants used to treat malaria and helminthic parasites and to evaluate their antimalarial and antischistosomal efficacy both in vivo and in vitro against malaria and schistosomiasis. These sites also provide vast exposure to virgin rain forests and the ability to conduct relevant research in environmental microbiology, ethnobotany and pharmacology. Sites in Italy provide expertise in cell biology, molecular biology and genetics. Through the Undergraduate Research Enhancement Program (UREP), undergraduates with strong academic background and motivation will work in discipline-based research teams of two-four students, led by a committed faculty mentor. Under the Pre-doctoral International Enrichment Program (PIE), candidates working in cutting-edge fields - cell, molecular, developmental biology, immunology, nanotechnology- will pursue independent or guided research. Data derived from this research may be utilized as part of the candidate's dissertation. Simultaneously, U.S. faculty mentors and their students are expected to develop strong collaborative programs with international scientists. Each MHIRT trainee will present his/her research data and findings in poster/platform presentations, workshop format or as publications. The proposed program is a formula for success for both the student and faculty, and should enhance the undergraduate-to-graduate transition and prepare more underrepresented groups for leadership roles in the biomedical sciences.