ROCKY MOUNTAIN REGIONAL CLINICAL TRIALS NODE

落基山区域临床试验节点

• 批准号: 7029121
• 负责人: Paula DeGraffenreid Riggs
• 金额: $ 142.76万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-30 至 2007-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7029121
• 关键词: clinical research; clinical trials; community health services; cooperative study; drug abuse; drug abuse therapy; human subject; human therapy evaluation

In this country, more patients are treated for alcohol and drug abuse by community-based treatment programs than by any other provider. While community treatment programs (CTPs) have a long history of providing quality treatment to large and diverse patient populations, their treatment approaches typically are not based on the latest evidence from the scientific literature. On the other hand, scientifically tested treatments, delivered under carefully controlled situations to highly selected patient groups, may not have applicability under usual care conditions. There is an urgent need to determine if research findings obtained in resource-rich universities are valid in community-based settings. The purpose of this application is to create a Rocky Mountain Regional (RMR) Clinical Trials Node to pursue this goal. Specifically, we offer the expertise of the substance abuse researchers in the Department of Psychiatry at the University of Colorado Health Sciences Center and the treatment providers we have been affiliated with for many years. Five of these providers are committed to participating in year one of the RMR Node and five more in year two, including CTPs from the state of Utah. Our affiliated treatment providers treat a broad array of clients with substance use problems in a variety of treatment modalities. We are committed to working in true partnership with Colorado and Utah CTPs and to working collaboratively with other investigators in NIDA's Clinical Trials Network (CTN), and with officials from NIDA. We have extensive and broad experience in multi-site collaborations, including multi-site clinical trials. We have expertise in a variety of behavioral and pharmacological treatment approaches, including motivational enhancement therapy, one of the interventions the CTN will be testing in the upcoming year. Our knowledge of this intervention in motivating out-of-treatment injection drug users to enter and remain in treatment would be of great benefit to the CTN.

在这个国家，更多的患者因酗酒和吸毒而接受治疗 以社区为基础的治疗方案比任何其他提供者都要多。而社区 治疗计划(CTP)在提供高质量治疗方面有很长的历史 患者群体庞大多样，他们的治疗方法通常是 不是基于科学文献中的最新证据。另一方面 经过科学测试的手工治疗方法，在严格控制下提供 对于高度精选的患者群体的情况，可能不适用于 通常的护理条件。迫切需要确定研究是否 在资源丰富的大学中获得的研究结果在社区基础上是有效的 设置。这个应用程序的目的是创建一个落基山脉 区域(RMR)临床试验节点以追求这一目标。具体地说，我们提供 美国司法部药物滥用研究人员的专业知识 科罗拉多大学健康科学中心的精神病学和 我们与治疗提供商有多年的合作关系。其中五个 提供商承诺参与RMR节点的第一年和第五年 第二年会有更多，包括犹他州的CTP。我们的附属公司 治疗提供者治疗大量有药物使用问题的客户 在各种治疗方式中。我们致力于在True工作 与科罗拉多州和犹他州CTP建立伙伴关系，并与 NIDA临床试验网络(CTN)的其他研究人员，以及官员 来自NIDA。我们在多站点协作方面拥有广泛的经验， 包括多点临床试验。我们在各种领域都有专业知识 行为和药物治疗方法，包括激励性 增强疗法，CTN将在 即将到来的一年。我们对这种激励干预的认识 退出治疗的注射吸毒者进入并继续接受治疗的将是 对CTN有很大的好处。